{"id":"W2004324618","doi":"10.4161/viru.2.3.15894","title":"A comprehensive study of the contribution of<i>Salmonella enterica</i>serovar Typhimurium SPI2 effectors to bacterial colonization, survival, and replication in typhoid fever, macrophage, and epithelial cell infection models","year":2011,"lang":"en","type":"article","venue":"Virulence","topic":"Salmonella and Campylobacter epidemiology","field":"Agricultural and Biological Sciences","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Michael Smith Health Research BC; University of British Columbia","funders":"Canadian Institutes of Health Research; Howard Hughes Medical Institute","keywords":"Salmonella enterica; Biology; Salmonella; Microbiology; Typhoid fever; Virulence; Effector; Virology; Pathogenicity island; Serotype; Salmonella typhi; Type three secretion system; Bacteria; Immunology; Escherichia coli; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002635465,0.0001099958,0.0002408937,0.00001943278,0.00006595554,0.000007896905,0.0001214741,0.00007825832,0.00001281718],"category_scores_gemma":[0.00009645952,0.00004987098,0.00002606534,0.0003255442,0.00007973006,0.00007831927,0.0001171226,0.0000648792,0.000001576297],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001504598,"about_ca_system_score_gemma":0.000005470226,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00287575,"about_ca_topic_score_gemma":0.0005378872,"domain_scores_codex":[0.9987823,0.0003812759,0.0003017354,0.0003101508,0.00009001546,0.0001345058],"domain_scores_gemma":[0.9993317,0.0001716201,0.000199504,0.0001191774,0.0001332607,0.00004476181],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001831127,0.0001819983,0.3836496,0.000008745384,0.000005250351,3.809266e-7,0.0003445143,0.00002088708,0.6147225,0.00003637473,0.000007024444,0.0008395633],"study_design_scores_gemma":[0.0003757628,0.0006610766,0.9507753,0.00001691104,0.00001427962,0.000002254088,0.0001066404,0.0001272704,0.04753629,0.0002161571,0.00008705971,0.00008102703],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988952,0.00006500552,0.0000388861,0.00003155216,0.0002515788,0.0006511358,0.00002656598,0.00001166031,0.00002842263],"genre_scores_gemma":[0.9997092,0.0001536307,0.00002298148,0.0000393592,0.00003350502,0.0000242911,0.000008676435,0.00000123097,0.000007089697],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5671862,"threshold_uncertainty_score":0.4347293,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03299148189463427,"score_gpt":0.2370558399593111,"score_spread":0.2040643580646768,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}