{"id":"W2004324618","doi":"10.4161/viru.2.3.15894","title":"A comprehensive study of the contribution of<i>Salmonella enterica</i>serovar Typhimurium SPI2 effectors to bacterial colonization, survival, and replication in typhoid fever, macrophage, and epithelial cell infection models","year":2011,"lang":"en","type":"article","venue":"Virulence","topic":"Salmonella and Campylobacter epidemiology","field":"Agricultural and Biological Sciences","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Michael Smith Health Research BC; University of British Columbia","funders":"Canadian Institutes of Health Research; Howard Hughes Medical Institute","keywords":"Salmonella enterica; Biology; Salmonella; Microbiology; Typhoid fever; Virulence; Effector; Virology; Pathogenicity island; Serotype; Salmonella typhi; Type three secretion system; Bacteria; Immunology; Escherichia coli; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001989891,0.0004935426,0.0003269662,0.0002065493,0.0001232343,0.0001563099,0.0001523908,0.0002129728,0.0003111179],"category_scores_gemma":[0.00008207274,0.0001118408,0.0004008069,0.0001394187,0.0001594894,0.0001864683,0.0001801757,0.0003091098,0.0001237908],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001660606,"about_ca_system_score_gemma":0.0002125207,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006177397,"about_ca_topic_score_gemma":0.0006962121,"domain_scores_codex":[0.9998902,0.0000249411,0.00001225068,0.00001908877,0.0000299223,0.00002361329],"domain_scores_gemma":[0.9999228,0.000009337166,0.00001839387,0.00001017901,0.00001715722,0.00002225102],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00008745406,0.00001775604,0.0002556369,0.00005258839,0.000005017107,0.00002382167,0.000008125749,0.00005922695,0.9987551,0.00001706502,0.00001638316,0.000701811],"study_design_scores_gemma":[0.00001371616,0.001930208,0.01092045,0.00001459591,0.00007505641,0.0004373868,0.00005785954,0.0008998325,0.9824537,0.00003216419,0.003155671,0.000009403159],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928912,0.003149224,0.002735646,0.00005004735,0.00001543005,0.00002709008,0.0003686625,0.00004603618,0.0007168577],"genre_scores_gemma":[0.9893718,0.003813373,0.003683308,0.00006081604,0.00001010653,0.00003971993,0.001549371,0.00002230629,0.001449182],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006177397,"threshold_uncertainty_score":0.001228273,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03299148189463427,"score_gpt":0.2370558399593111,"score_spread":0.2040643580646768,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}