{"id":"W2004439872","doi":"10.1126/scitranslmed.3010262","title":"Human Cells: Finally Open for Cancer Business","year":2014,"lang":"en","type":"article","venue":"Science Translational Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Insertional mutagenesis; Transposable element; Lentivirus; Mutagenesis; Cancer cell; Cancer; Biology; Computational biology; Cancer research; Genetics; Cell biology; Mutation; Gene; Genome; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008210901,0.0007243683,0.0009181669,0.001174808,0.001450611,0.008392957,0.001748262,0.006603199,0.05837873],"category_scores_gemma":[0.01005459,0.0004912962,0.001103951,0.001102269,0.002823976,0.007868119,0.004945503,0.00952563,0.0430577],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001510336,"about_ca_system_score_gemma":0.004031463,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001262585,"about_ca_topic_score_gemma":0.001659164,"domain_scores_codex":[0.9970595,0.0006827505,0.0001534681,0.0002923085,0.00145512,0.0003568871],"domain_scores_gemma":[0.9890947,0.001836598,0.0003430047,0.002070589,0.002931172,0.003723929],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002055158,0.00009824194,0.0004554625,0.0001936982,0.0000277422,0.0003117017,0.0003203592,0.000145713,0.003771312,0.1221614,0.7109098,0.1613992],"study_design_scores_gemma":[0.00001735109,0.00003314343,0.00007845788,0.00005041851,0.000004630893,0.0001034917,0.00009087916,0.00005173558,0.0008577922,0.01173751,0.9869679,0.000006647438],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.005978372,0.07093325,0.06423082,0.513001,0.07011136,0.000447188,0.006186185,0.009120981,0.2599908],"genre_scores_gemma":[0.06667203,0.07932716,0.07703826,0.1547037,0.02330905,0.0007754423,0.01208549,0.004271281,0.5818176],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.05837873,"threshold_uncertainty_score":0.1952963,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02398351524501828,"score_gpt":0.3860925311607041,"score_spread":0.3621090159156858,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}