{"id":"W2004451473","doi":"10.2217/pgs.09.112","title":"Mitochondrial Gene Profiling: Translational Perspectives","year":2009,"lang":"en","type":"review","venue":"Pharmacogenomics","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Mitochondrial disease; Computational biology; Biology; Disease; Gene expression profiling; DNA microarray; Bioinformatics; Microarray; Drug development; Gene; Mitochondrion; Medicine; Mitochondrial DNA; Drug; Genetics; Gene expression; Pharmacology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001162111,0.0004762377,0.0007720768,0.0001256476,0.0001090391,0.00003388416,0.0003476609,0.0005057951,0.0001791469],"category_scores_gemma":[0.00003925896,0.0004564966,0.0007087593,0.0001223513,0.00007268584,0.000003304571,0.0000543613,0.0003394733,0.0001399128],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003907826,"about_ca_system_score_gemma":0.0004872179,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":9.519842e-7,"about_ca_topic_score_gemma":0.00000118926,"domain_scores_codex":[0.9980184,0.0002106739,0.0005118692,0.0007919447,0.0001343859,0.0003326531],"domain_scores_gemma":[0.9991398,0.00002337736,0.0002364645,0.0003614322,0.00008983993,0.0001491212],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002737428,0.000241461,0.000001609771,0.00101826,0.0006549787,0.00002863714,0.000110169,0.00003048235,0.09889022,0.0005205647,0.007382732,0.8908471],"study_design_scores_gemma":[0.0005416235,0.0001060864,1.254551e-7,0.00007475387,0.0004921321,0.0001862992,0.000009580911,0.000004547866,0.003497867,0.00003413194,0.9945909,0.0004619634],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003754307,0.9937984,0.001793683,0.00002815703,0.001572717,0.0008562464,0.000330708,0.00003116769,0.00155143],"genre_scores_gemma":[0.000003747732,0.9835814,0.0062723,0.0001479497,0.006213187,0.00008524262,0.002467985,0.00007818262,0.001149994],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9872081,"threshold_uncertainty_score":0.9997887,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04733656746589832,"score_gpt":0.3445592195094189,"score_spread":0.2972226520435206,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}