{"id":"W2004466150","doi":"10.1016/s0014-5793(03)01023-8","title":"Differential interaction of the two cholesterol‐dependent, membrane‐damaging toxins, streptolysin O and <i>Vibrio cholerae</i> cytolysin, with enantiomeric cholesterol","year":2003,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; U.S. Public Health Service; National Institutes of Health","keywords":"Cytolysin; Streptolysin; Vibrio cholerae; Cholesterol; Cholera toxin; Liposome; Microbiology; Chemistry; Toxin; Membrane; Biochemistry; Biology; Bacteria; Bacterial protein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001175415,0.000263863,0.0002631263,0.00008106412,0.0001620977,0.0001040648,0.0002379854,0.00005591884,0.00001784452],"category_scores_gemma":[0.00004489192,0.0001850532,0.00009612594,0.00016619,0.0002701725,0.00002889271,0.0001886573,0.000205706,0.000002721201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002671919,"about_ca_system_score_gemma":0.000033992,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000760655,"about_ca_topic_score_gemma":0.0001348805,"domain_scores_codex":[0.9983923,0.000218682,0.0002644603,0.0004653267,0.0002956112,0.0003636221],"domain_scores_gemma":[0.999143,0.00001739688,0.0001948384,0.0005085455,0.00005859342,0.000077642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009723179,0.00005299483,0.02708969,0.00004213479,0.0001680037,0.000002758823,0.0001197541,0.00006334601,0.971487,0.000006474142,0.0002006517,0.0006699361],"study_design_scores_gemma":[0.002120205,0.0001293568,0.05573,0.00008582524,0.00006708709,0.00008811353,0.0001404211,0.00002225093,0.9378862,0.000001556684,0.003477715,0.0002512316],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976031,0.00007449012,0.0006197098,0.0009557503,0.0002440865,0.0002923095,0.00001573811,0.00001291104,0.0001818665],"genre_scores_gemma":[0.9985753,0.00008941425,0.0001188082,0.0008606382,0.0001138857,0.00002749055,0.00002794476,0.00003431651,0.0001521448],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03360079,"threshold_uncertainty_score":0.7546251,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007667977331069421,"score_gpt":0.2369823813226837,"score_spread":0.2293144039916143,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}