{"id":"W2004555055","doi":"10.2174/187221309789257423","title":"Selective Chemokine Receptor-Targeted Depletion of Pathological Cells as A Therapeutic Strategy for Inflammatory, Allergic and Autoimmune Diseases","year":2009,"lang":"en","type":"review","venue":"Recent Patents on Inflammation & Allergy Drug Discovery","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"St Mary's Hospital","funders":"","keywords":"Monoclonal antibody; Chemokine receptor; Immunology; Chemokine; CCR1; Chemokine receptor CCR5; Antibody; Cancer research; Inflammation; Medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003357751,0.0006655256,0.001001785,0.002030781,0.0002172346,0.0004935351,0.0005748941,0.0007316333,0.003032217],"category_scores_gemma":[0.0002037713,0.0001893226,0.000384195,0.001574573,0.0003022556,0.0007622463,0.0002956849,0.0008148677,0.001975658],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005002627,"about_ca_system_score_gemma":0.0005124793,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004826728,"about_ca_topic_score_gemma":0.001017051,"domain_scores_codex":[0.9998803,0.0000124505,0.00001127442,0.00001867675,0.00006237091,0.00001488156],"domain_scores_gemma":[0.9999257,0.000028194,0.00001482604,0.000002419828,0.00002005455,0.000008885658],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001184355,0.0002147099,0.0001761915,0.008369836,0.00007404709,0.0006951097,0.0000613663,0.0004942267,0.02532537,0.004541001,0.01832122,0.9416085],"study_design_scores_gemma":[0.00007757975,0.0003822676,0.001283533,0.001122875,0.0001400226,0.00408357,0.00005881756,0.0002293057,0.01018681,0.001676656,0.9807329,0.00002559507],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001668664,0.9920601,0.0007232937,0.0003013789,0.0002825391,0.00002292707,0.00003467002,0.00002818282,0.004878245],"genre_scores_gemma":[0.004115407,0.9908159,0.000819747,0.0002872587,0.0001674064,0.00002692347,0.00006547206,0.000003309712,0.003698554],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003032217,"threshold_uncertainty_score":0.01014376,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04620122271028462,"score_gpt":0.3312707757642936,"score_spread":0.285069553054009,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}