{"id":"W2004629447","doi":"10.1038/onc.2011.292","title":"Telomerase promotes efficient cell cycle kinetics and confers growth advantage to telomerase-negative transformed human cells","year":2011,"lang":"en","type":"article","venue":"Oncogene","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Telomerase; Telomere; Biology; Telomerase reverse transcriptase; Carcinogenesis; Cell cycle; Oncogene; Telomerase RNA component; Cell growth; Cell biology; Cell; Cancer research; Genetics; DNA; Cancer; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003479828,0.0002694308,0.0002470043,0.0005112542,0.0001892156,0.0005310694,0.0001872283,0.0001589408,0.001812793],"category_scores_gemma":[0.0004284616,0.000181785,0.0002201808,0.0002963332,0.0001844228,0.0002384291,0.0001899768,0.0004844134,0.0007363222],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002088068,"about_ca_system_score_gemma":0.0003119198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004336501,"about_ca_topic_score_gemma":0.0006313057,"domain_scores_codex":[0.9998922,0.00002215126,0.00001425468,0.00001993002,0.00002938808,0.0000218689],"domain_scores_gemma":[0.999668,0.00009106333,0.00005062187,0.0000840748,0.00003559907,0.00007059932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002577583,0.00004009089,0.0003267061,0.00001563354,0.000002879618,0.00004811645,0.00002961574,0.00005088434,0.995499,0.0003116577,0.00009737223,0.003320331],"study_design_scores_gemma":[0.00003636331,0.0004050686,0.002895248,0.000005132155,0.00001583179,0.0005202811,0.00001654008,0.000610235,0.9905089,0.0002174501,0.0047639,0.000005065336],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9836175,0.004902379,0.005976855,0.0001514923,0.00006954964,0.00002675398,0.0004785589,0.0004282575,0.004348622],"genre_scores_gemma":[0.9903785,0.001376963,0.001670228,0.000033812,0.00003096101,0.00001452962,0.0006150018,0.000072689,0.00580733],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001812793,"threshold_uncertainty_score":0.006064355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02058234073954252,"score_gpt":0.2561426559489604,"score_spread":0.2355603152094179,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}