{"id":"W2004635464","doi":"10.1097/00002030-200301030-00005","title":"Agent and cell-type specificity in the induction of insulin resistance by HIV protease inhibitors","year":2003,"lang":"en","type":"article","venue":"AIDS","topic":"HIV-related health complications and treatments","field":"Medicine","cited_by":97,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"Israel Science Foundation","keywords":"GLUT4; Glucose transporter; Glucose uptake; GLUT1; Internal medicine; Endocrinology; Insulin; Insulin resistance; Snf3; Glucose Transporter Type 1; Biology; Nelfinavir; Protein kinase B; Troglitazone; Insulin receptor; Phosphorylation; Biochemistry; Medicine; Peroxisome proliferator-activated receptor; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001718974,0.00005388446,0.0000929326,0.00004587563,0.00004655403,0.000003089687,0.00002298888,0.00004522796,0.00002115226],"category_scores_gemma":[0.00004467023,0.00003751622,0.00001230744,0.0002785389,0.00003259508,0.00002344718,0.000004105241,0.0001187824,0.00001458607],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003944638,"about_ca_system_score_gemma":0.00004308261,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004954539,"about_ca_topic_score_gemma":0.000003390528,"domain_scores_codex":[0.9994605,0.00007003265,0.0001728076,0.0001151442,0.00009816558,0.00008330903],"domain_scores_gemma":[0.9996685,0.00002440244,0.00005338276,0.0001753171,0.00003756882,0.00004079797],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006398386,0.00451559,0.8864087,0.0006157605,0.00006977749,0.00004942973,0.006207532,0.000007586615,0.02386721,0.0080678,0.05804418,0.01150659],"study_design_scores_gemma":[0.009279169,0.001936848,0.6135051,0.0006672917,0.0001955438,0.0000480624,0.00277548,0.00003748138,0.06499788,0.002613476,0.3035701,0.0003735111],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991071,0.001400419,0.00002213847,0.0006438154,0.00003469335,0.0004952537,0.000005118944,0.000006542466,0.006321061],"genre_scores_gemma":[0.9982093,0.0001931751,0.0005973918,0.00008016261,0.00001326659,0.00002612974,0.00001336877,0.000004907964,0.0008623158],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2729036,"threshold_uncertainty_score":0.1529867,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0205073973759646,"score_gpt":0.2766611617139659,"score_spread":0.2561537643380013,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}