{"id":"W2004639015","doi":"10.1016/j.ccr.2009.05.013","title":"Gli2 and p53 Cooperate to Regulate IGFBP-3- Mediated Chondrocyte Apoptosis in the Progression from Benign to Malignant Cartilage Tumors","year":2009,"lang":"en","type":"article","venue":"Cancer Cell","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Chondrocyte; Cartilage; Cancer research; Apoptosis; Medicine; Biology; Anatomy; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002335862,0.0002304196,0.0002094795,0.00006643835,0.0000927018,0.00007003297,0.0003563442,0.0001698889,0.0000585113],"category_scores_gemma":[0.00004203642,0.0001796728,0.00005092236,0.0003420677,0.00003408749,0.000006905,0.0001376789,0.0001639877,0.00001835988],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000733714,"about_ca_system_score_gemma":0.0001432325,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003697253,"about_ca_topic_score_gemma":0.0006872692,"domain_scores_codex":[0.9981989,0.0001337503,0.0002439851,0.0006417877,0.0002986374,0.0004830007],"domain_scores_gemma":[0.9990963,0.0000127967,0.00005165297,0.0005006819,0.00009460359,0.0002439788],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002936302,0.00004219533,0.00001958348,0.000008970666,0.000008037075,0.00002002406,0.0004526892,0.0004962474,0.9922555,0.000009229847,0.002017385,0.004376476],"study_design_scores_gemma":[0.0006894791,0.0005241288,0.0003823028,0.00009304372,0.00001508212,0.000002990946,0.0001541391,0.00009815623,0.9791182,0.00001835199,0.01865467,0.0002494752],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922811,0.003856506,0.000544647,0.001543208,0.0001209323,0.0009175089,0.00008224509,0.00001612908,0.0006377678],"genre_scores_gemma":[0.9953169,0.000818821,0.0003491699,0.002667282,0.0001464236,0.0002011567,0.0001089918,0.00003252591,0.0003587307],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01663728,"threshold_uncertainty_score":0.7326845,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00862866655651611,"score_gpt":0.2759832101948816,"score_spread":0.2673545436383655,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}