{"id":"W2004639015","doi":"10.1016/j.ccr.2009.05.013","title":"Gli2 and p53 Cooperate to Regulate IGFBP-3- Mediated Chondrocyte Apoptosis in the Progression from Benign to Malignant Cartilage Tumors","year":2009,"lang":"en","type":"article","venue":"Cancer Cell","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Chondrocyte; Cartilage; Cancer research; Apoptosis; Medicine; Biology; Anatomy; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001748565,0.0002806018,0.0002239781,0.0005719434,0.0002803374,0.0003936955,0.0002146279,0.0002184738,0.0009815955],"category_scores_gemma":[0.0001990979,0.0002381234,0.0002878101,0.0002466892,0.0002650293,0.0002459611,0.0003090971,0.0003879448,0.0004451917],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005129825,"about_ca_system_score_gemma":0.0003719045,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002833009,"about_ca_topic_score_gemma":0.003491143,"domain_scores_codex":[0.9998217,0.00002590545,0.00001205741,0.00001453421,0.00005562054,0.00007021225],"domain_scores_gemma":[0.9998701,0.00001538952,0.00003310161,0.00001785403,0.00002779418,0.00003579837],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005128815,0.0000222704,0.003647564,0.00003178578,0.00001296604,0.0003722428,0.00002846255,0.00006700974,0.993115,0.0001876076,0.0001175379,0.001884724],"study_design_scores_gemma":[0.00006793159,0.0003210846,0.1322193,0.000005558908,0.00005476821,0.002086055,0.0001524612,0.001601579,0.860487,0.0002448934,0.00274742,0.00001193382],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938601,0.002477202,0.001659093,0.0001290379,0.00002353853,0.00001402161,0.000205917,0.00009555852,0.001535433],"genre_scores_gemma":[0.9973457,0.0003841421,0.0004349756,0.0000263057,0.000004776587,0.00001023205,0.000156545,0.000007131239,0.001630201],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002833009,"threshold_uncertainty_score":0.005633056,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00862866655651611,"score_gpt":0.2759832101948816,"score_spread":0.2673545436383655,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}