{"id":"W2004728197","doi":"10.1007/s10350-006-0568-4","title":"Tumor Buds Show Reduced Expression of Laminin-5 Gamma 2 Chain in DNA Mismatch Repair Deficient Colorectal Cancer","year":2006,"lang":"en","type":"article","venue":"Diseases of the Colon & Rectum","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"MLH1; Colorectal cancer; Medicine; Tumor budding; Mouse model of colorectal and intestinal cancer; Cancer research; DNA methylation; Cancer; Oncology; Internal medicine; Pathology; DNA mismatch repair; Biology; Gene expression; Metastasis; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007657514,0.0001683025,0.0001372229,0.0004247548,0.0001348923,0.0001787329,0.0001041961,0.0001590685,0.001116582],"category_scores_gemma":[0.0001940788,0.0001442948,0.00009869155,0.0001820334,0.0001841352,0.00008788089,0.0002144043,0.0001455626,0.0002317545],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001852946,"about_ca_system_score_gemma":0.00009011421,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006805686,"about_ca_topic_score_gemma":0.000971965,"domain_scores_codex":[0.9999291,0.000008246046,0.000006470088,0.00001422999,0.00002526339,0.00001670749],"domain_scores_gemma":[0.9998146,0.00002927054,0.00008103433,0.00001326652,0.00001760677,0.00004419487],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001074653,0.00003698815,0.1795419,0.00007994752,0.00003787757,0.00343441,0.0001502157,0.0001334018,0.8114398,0.00007849606,0.0001262786,0.003866054],"study_design_scores_gemma":[0.00002654746,0.0004349732,0.8615164,0.000008355434,0.00004330522,0.01534393,0.0002163544,0.0005276572,0.121041,0.00005579516,0.0007786012,0.000006943088],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995364,0.0001509892,0.000101107,0.000004076107,0.000001021433,0.000001736515,0.00002777733,0.000007387368,0.0001693951],"genre_scores_gemma":[0.9995015,0.00006929268,0.0001436293,0.000004949265,8.663509e-7,0.000001950483,0.00009556254,0.000002045575,0.0001802934],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001116582,"threshold_uncertainty_score":0.003735304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01062232654303553,"score_gpt":0.2753585845127855,"score_spread":0.26473625796975,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}