{"id":"W2004733722","doi":"10.1002/cbic.201190016","title":"Inside Cover: Different Active‐Site Loop Orientation in Serine Hydrolases versus Acyltransferases (ChemBioChem 5/2011)","year":2011,"lang":"en","type":"paratext","venue":"ChemBioChem","topic":"Amino Acid Enzymes and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute; McGill University","funders":"","keywords":"Active site; Oxyanion hole; Hydrolase; Pseudomonas fluorescens; Chemistry; Serine; Acyltransferases; Acyltransferase; Esterase; Stereochemistry; Serine hydrolase; Biochemistry; Enzyme; Biology; Biosynthesis; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001199581,0.001102256,0.00100494,0.0002227247,0.0001066687,0.0000621369,0.0006120474,0.001048601,0.002194679],"category_scores_gemma":[0.00008854832,0.001109699,0.0004489038,0.0002085335,0.0002289762,0.00002389437,0.000372033,0.0006330094,0.001720577],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000138413,"about_ca_system_score_gemma":0.0002792544,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002395201,"about_ca_topic_score_gemma":0.0001101163,"domain_scores_codex":[0.996338,0.00009343233,0.0007452947,0.00154563,0.0003809437,0.0008967254],"domain_scores_gemma":[0.9979354,0.00004296,0.0003524857,0.001164037,0.0001880724,0.0003170124],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002651862,0.0006256227,0.0001977424,0.0003631557,0.0004099671,0.00002625859,0.000281813,0.00003109735,0.9046522,0.0000190547,0.08834587,0.002395333],"study_design_scores_gemma":[0.003653649,0.0003577427,0.0006180489,0.0001060339,0.0001485714,0.00001662528,0.0001146672,0.000008814701,0.8650666,0.00000669594,0.1288671,0.001035443],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9417919,0.008633194,0.0001087008,0.00003902972,0.002611493,0.0006603844,0.0006882796,0.00003843794,0.04542861],"genre_scores_gemma":[0.9168257,0.01037227,0.0001116577,0.0002673962,0.001399012,0.000229126,0.01197339,0.0002073008,0.05861418],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04052126,"threshold_uncertainty_score":0.9991353,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01580053147118017,"score_gpt":0.2526207415233857,"score_spread":0.2368202100522055,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}