{"id":"W2004755165","doi":"10.1097/shk.0b013e318157ebc8","title":"NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (REDUCED FORM) OXIDASE IS IMPORTANT FOR LPS-INDUCED ENDOTHELIAL CELL ACTIVATION","year":2008,"lang":"en","type":"article","venue":"Shock","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal Victoria Hospital; McGill University Health Centre","funders":"","keywords":"NADPH oxidase; Nicotinamide adenine dinucleotide phosphate; Chemistry; Apocynin; Superoxide; Biochemistry; Cell biology; Umbilical vein; Oxidase test; Intracellular; Molecular biology; Biology; Reactive oxygen species; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000225318,0.0004042407,0.000476204,0.0001463962,0.0005120619,0.00001703436,0.0003196441,0.0002859774,0.000886048],"category_scores_gemma":[0.00009420072,0.0003583429,0.0002587437,0.0001819656,0.00009674831,0.0002591801,0.00009711258,0.0003247621,0.000465786],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009948388,"about_ca_system_score_gemma":0.0001472552,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000915847,"about_ca_topic_score_gemma":0.00001083922,"domain_scores_codex":[0.9978935,0.0001049277,0.0005824426,0.0006141504,0.00008103741,0.0007239805],"domain_scores_gemma":[0.9988354,0.0001724434,0.0003203009,0.0004433811,0.0001559655,0.00007254272],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007559813,0.0001716413,0.0001453981,0.00002541518,0.00009860055,0.00001714115,0.0005506749,9.510768e-7,0.9900582,0.0006688045,0.006454532,0.001052609],"study_design_scores_gemma":[0.003626622,0.000643594,0.0006737194,0.00003137496,0.00005705683,0.0000748266,0.0001405433,0.00001690352,0.9775467,0.0008700465,0.01589869,0.0004199445],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949638,0.0002866737,0.001576554,0.0006473808,0.0007541413,0.0009446886,0.0002105824,0.0001565428,0.0004596066],"genre_scores_gemma":[0.9895615,0.0001315757,0.0008928354,0.001235212,0.0001591226,0.00009984123,0.000272505,0.00007337554,0.007574051],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01251158,"threshold_uncertainty_score":0.9998869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02340479063634133,"score_gpt":0.2401712530657237,"score_spread":0.2167664624293824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}