{"id":"W2004755165","doi":"10.1097/shk.0b013e318157ebc8","title":"NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (REDUCED FORM) OXIDASE IS IMPORTANT FOR LPS-INDUCED ENDOTHELIAL CELL ACTIVATION","year":2008,"lang":"en","type":"article","venue":"Shock","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal Victoria Hospital; McGill University Health Centre","funders":"","keywords":"NADPH oxidase; Nicotinamide adenine dinucleotide phosphate; Chemistry; Apocynin; Superoxide; Biochemistry; Cell biology; Umbilical vein; Oxidase test; Intracellular; Molecular biology; Biology; Reactive oxygen species; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002116356,0.000237999,0.0001518567,0.0001107984,0.0001331266,0.0003159961,0.0001454698,0.0002684816,0.0008702675],"category_scores_gemma":[0.0002686027,0.00009563982,0.0001368054,0.00006747427,0.0001720228,0.0001822024,0.0001312821,0.0004749464,0.0002432554],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002740502,"about_ca_system_score_gemma":0.0002218151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004313549,"about_ca_topic_score_gemma":0.0004498065,"domain_scores_codex":[0.9998441,0.00004524676,0.000009801493,0.00002166692,0.00004838674,0.00003088052],"domain_scores_gemma":[0.9998738,0.00001796392,0.00003669717,0.00001104955,0.00003087907,0.00002958985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002398763,0.00003761414,0.0006021902,0.00004802648,0.000005227196,0.0001096831,0.00001127681,0.00003219232,0.9953578,0.000210109,0.00008924506,0.003256764],"study_design_scores_gemma":[0.00005515237,0.0005564315,0.03453473,0.00003213468,0.00004080456,0.001158576,0.00007195015,0.002116338,0.9506884,0.000795248,0.009940781,0.000009534833],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9686548,0.01688318,0.01046531,0.0009020562,0.0001393973,0.00004713387,0.0002172743,0.0001215864,0.002569311],"genre_scores_gemma":[0.9922487,0.00296912,0.002602348,0.00007037907,0.00002574093,0.00002324614,0.000224457,0.0000087842,0.001827281],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008702675,"threshold_uncertainty_score":0.002911329,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02340479063634133,"score_gpt":0.2401712530657237,"score_spread":0.2167664624293824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}