{"id":"W2004836183","doi":"10.1158/0008-5472.sabcs10-p3-14-15","title":"Abstract P3-14-15: Lapatinib Plus Capecitabine in Trastuzumab Pre-Treated HER2- Positive Metastatic Breast Cancer: The Canadian Lapatinib Expanded Access Program Experience","year":2010,"lang":"en","type":"article","venue":"Cancer Research","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Northeast Cancer Centre; Hôpital Charles-Le Moyne; Regional Municipality of Durham; CancerCare Manitoba; BC Cancer Agency","funders":"","keywords":"Lapatinib; Medicine; Capecitabine; Trastuzumab; Internal medicine; Metastatic breast cancer; Taxane; Oncology; Breast cancer; Cancer; Progressive disease; Gastroenterology; Tyrosine-kinase inhibitor; Chemotherapy; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005082493,0.000238675,0.0002322287,0.0001858276,0.0006474497,0.0004792067,0.0005529391,0.000252671,0.002386875],"category_scores_gemma":[0.0007420643,0.00008547576,0.0002001031,0.0005920657,0.0003440003,0.0001459584,0.0003725661,0.000559533,0.000195325],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.008191962,"about_ca_system_score_gemma":0.01172569,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.5824071,"about_ca_topic_score_gemma":0.7388324,"domain_scores_codex":[0.9997651,0.00004436117,0.000008787462,0.00003040168,0.00007491,0.00007631837],"domain_scores_gemma":[0.9993493,0.00005956287,0.0000436458,0.00001332844,0.000120008,0.0004141879],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.03194999,0.01092234,0.3954128,0.0007078422,0.0003810498,0.002950927,0.001906616,0.002829393,0.01845803,0.0009141693,0.0201783,0.5133886],"study_design_scores_gemma":[0.007588032,0.03324031,0.8842183,0.0002170875,0.0003175694,0.002978472,0.0009809358,0.002045561,0.003971002,0.000141982,0.06425344,0.00004739012],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890684,0.002026372,0.0002093067,0.0005757512,0.00002127244,0.0003365437,0.0006156238,0.00001762459,0.007129075],"genre_scores_gemma":[0.9935297,0.001886303,0.0006364768,0.0003966884,0.00004877233,0.00008283788,0.001105942,0.000009642305,0.002303516],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4175929,"threshold_uncertainty_score":0.8401043,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06690299879045916,"score_gpt":0.4538422047316935,"score_spread":0.3869392059412343,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}