{"id":"W2004844436","doi":"10.1021/ac035231d","title":"Open Tubular Immobilized Metal Ion Affinity Chromatography Combined with MALDI MS and MS/MS for Identification of Protein Phosphorylation Sites","year":2004,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Mass Spectrometry Techniques and Applications","field":"Chemistry","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Phosphopeptide; Phosphoprotein; Phosphorylation; Chromatography; Mass spectrometry; Protein phosphorylation; Tandem mass spectrometry; Protein mass spectrometry; Sample preparation in mass spectrometry; Matrix-assisted laser desorption/ionization; Peptide; Electrospray ionization; Biochemistry; Protein kinase A; Desorption; Adsorption; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005727801,0.001002113,0.0008139213,0.001066007,0.0004414783,0.000642402,0.001357534,0.0009117099,0.001677402],"category_scores_gemma":[0.000402997,0.0004142671,0.0005880396,0.0008901424,0.0004924695,0.0006374294,0.0006921475,0.0008562143,0.001823568],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005090759,"about_ca_system_score_gemma":0.0005309962,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009332413,"about_ca_topic_score_gemma":0.001630528,"domain_scores_codex":[0.9992507,0.00009955741,0.00003597905,0.0001322524,0.0004052766,0.00007627633],"domain_scores_gemma":[0.9997602,0.00004779193,0.00004031583,0.00002201638,0.00007882669,0.00005097497],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009168907,0.00003191265,0.0001582228,0.0001035279,0.00001431624,0.00007687505,0.00001110398,0.00007234157,0.9880617,0.0001441979,0.0001781695,0.01105597],"study_design_scores_gemma":[0.00002754512,0.0003109819,0.002227844,0.00001523526,0.00007283007,0.0014659,0.00002860898,0.005862032,0.9783886,0.000395344,0.01116838,0.0000367783],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.3343082,0.04628769,0.6024183,0.0009992342,0.0007302791,0.0005240445,0.0008714856,0.003946048,0.009914779],"genre_scores_gemma":[0.4299753,0.01968979,0.5327485,0.0006138086,0.0002775721,0.0003032747,0.001607266,0.0002406549,0.01454387],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.001677402,"threshold_uncertainty_score":0.00561142,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01287195129813515,"score_gpt":0.2645026633861151,"score_spread":0.2516307120879799,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}