{"id":"W2004925004","doi":"10.1371/journal.pone.0052287","title":"Apolipoprotein(a) Inhibits In Vitro Tube Formation in Endothelial Cells: Identification of Roles for Kringle V and the Plasminogen Activation System","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Windsor; Queen's University","funders":"Heart and Stroke Foundation of Canada","keywords":"Kringle domain; Angiostatin; Angiogenesis; Plasmin; Biochemistry; Apolipoprotein B; Chemistry; Molecular biology; Lipoprotein; Biology; Enzyme; Cancer research; Cholesterol","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001676521,0.0003647583,0.0002436448,0.0001476843,0.00009139058,0.0002081415,0.0001634616,0.0002298051,0.0005053222],"category_scores_gemma":[0.0001211902,0.0001049017,0.0002727203,0.00008837949,0.0001610027,0.0001010912,0.0001020706,0.0003146191,0.0002103533],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001726209,"about_ca_system_score_gemma":0.0001715498,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008360191,"about_ca_topic_score_gemma":0.0007638093,"domain_scores_codex":[0.9998978,0.00003928654,0.000009128005,0.000008216047,0.0000190041,0.00002656717],"domain_scores_gemma":[0.9998862,0.00004426748,0.00002204855,0.00001239824,0.00001236979,0.000022719],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003428567,0.000157064,0.0002381139,0.00005602752,0.000008548592,0.00006828469,0.00001993311,0.0000716225,0.9966816,0.00006127805,0.00003799108,0.002256517],"study_design_scores_gemma":[0.00007806873,0.002351427,0.00680217,0.000007551885,0.0000230859,0.0002816317,0.00001652141,0.001517916,0.9876903,0.00002959777,0.001196867,0.00000493094],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995356,0.002724856,0.0008704204,0.00004260322,0.00001913456,0.00002364141,0.00005680904,0.00003843848,0.0008682028],"genre_scores_gemma":[0.9958273,0.001596923,0.001304771,0.00003357842,0.00001797627,0.00002745687,0.0002185893,0.000007248047,0.0009663022],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008360191,"threshold_uncertainty_score":0.001690507,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0130735494666394,"score_gpt":0.1926631919448524,"score_spread":0.179589642478213,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}