{"id":"W2004928732","doi":"10.1002/1521-3773(20010216)40:4<779::aid-anie7790>3.0.co;2-1","title":"A Novel Approach for the One-Pot Preparation of α-Amino Amides by Pd-Catalyzed Double Carbohydroamination","year":2001,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Amine gas treating; Palladium; Catalysis; Chemistry; Carbonylation; Aryl; Domino; Combinatorial chemistry; Condensation; Iodide; Primary (astronomy); Organic chemistry; Carbon monoxide; Alkyl","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001663234,0.0001090362,0.0001153335,0.00003390476,0.00006748085,0.00002900162,0.0002027486,0.0001076788,0.00003529149],"category_scores_gemma":[0.0001021622,0.00009082387,0.0001477004,0.00008768084,0.00006303684,0.0000180934,0.00003931223,0.00004220822,9.233572e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003755592,"about_ca_system_score_gemma":0.00001756712,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008466085,"about_ca_topic_score_gemma":0.0000158273,"domain_scores_codex":[0.9991617,0.000006208184,0.0002380659,0.0002555998,0.0002266777,0.0001117576],"domain_scores_gemma":[0.9993462,0.00004452401,0.0001737318,0.0001712553,0.0002343574,0.00002991054],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002338675,0.0002228008,0.0001008262,0.00001288183,0.0001637823,3.89823e-8,0.00002896705,0.00009689495,0.9941265,0.00007164751,0.004254523,0.0006872487],"study_design_scores_gemma":[0.0007355873,0.00003256445,0.0001507309,0.00001015323,0.00007515441,0.00000353567,0.0000499359,0.002150828,0.985445,0.00006317479,0.01117741,0.0001059478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5519896,0.0004864171,0.4387628,0.001051037,0.000273464,0.0005099808,0.0003744797,0.00002342406,0.006528863],"genre_scores_gemma":[0.9917294,0.0002157675,0.000870491,0.00006331236,0.0007689983,0.0001810278,0.005337922,0.0000127089,0.0008203805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4397399,"threshold_uncertainty_score":0.370369,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02012087834123254,"score_gpt":0.2734198218195938,"score_spread":0.2532989434783613,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}