{"id":"W2004942012","doi":"10.1016/j.nbd.2015.03.022","title":"VEGF can protect against blood brain barrier dysfunction, dendritic spine loss and spatial memory impairment in an experimental model of diabetes","year":2015,"lang":"en","type":"article","venue":"Neurobiology of Disease","topic":"Neurological Disease Mechanisms and Treatments","field":"Neuroscience","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Michael Smith Health Research BC; Canada Foundation for Innovation; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Heart and Stroke Foundation of British Columbia and Yukon; Heart and Stroke Foundation of Canada","keywords":"Hippocampus; Dentate gyrus; Hippocampal formation; Morris water navigation task; Vascular endothelial growth factor; Dendritic spine; Neuroscience; Memory impairment; Vascular permeability; Diabetes mellitus; Medicine; Psychology; Internal medicine; Endocrinology; Cognition; VEGF receptors","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002610412,0.0003496495,0.0003899745,0.0003213195,0.0002363707,0.0003559625,0.0003014139,0.0005198345,0.001200909],"category_scores_gemma":[0.0002705447,0.000160411,0.0003715258,0.0002246017,0.0003588446,0.0005809776,0.0001743993,0.001147589,0.0001705837],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003993456,"about_ca_system_score_gemma":0.0004091452,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001234401,"about_ca_topic_score_gemma":0.000939972,"domain_scores_codex":[0.9998745,0.00002301003,0.0000110578,0.00001927866,0.00002089277,0.00005126054],"domain_scores_gemma":[0.9998366,0.00001842241,0.00005506082,0.00001842244,0.00001744944,0.00005404804],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008200649,0.0009670774,0.0007406659,0.000362979,0.00008275473,0.0003063057,0.00007140404,0.0004252192,0.9735932,0.001009981,0.0006865495,0.01355322],"study_design_scores_gemma":[0.0008662259,0.005037294,0.01013276,0.00007585035,0.0003181664,0.000706543,0.0001514351,0.002317704,0.9731507,0.0009588352,0.0062581,0.00002635064],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992617,0.004021822,0.001361546,0.000437136,0.0001512444,0.00002618949,0.0002094979,0.00007763858,0.001098014],"genre_scores_gemma":[0.9952338,0.001966913,0.0007394266,0.0001132699,0.00004916096,0.00003150411,0.0002559563,0.00001246287,0.001597528],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001234401,"threshold_uncertainty_score":0.004017472,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02437202364467199,"score_gpt":0.2510042537723748,"score_spread":0.2266322301277028,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}