{"id":"W2004948071","doi":"10.1371/journal.ppat.1003597","title":"Intact Type I Interferon Production and IRF7 Function in Sooty Mangabeys","year":2013,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Animal Disease Management and Epidemiology","field":"Agricultural and Biological Sciences","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Office of Research Infrastructure Programs, National Institutes of Health; National Center for Research Resources; National Institute of Allergy and Infectious Diseases; Yerkes National Primate Research Center, Emory University; National Institutes of Health; National Cancer Institute; Frederick National Laboratory for Cancer Research; Emory University","keywords":"IRF7; Biology; Interferon; TLR7; Exon; Virology; Interferon regulatory factors; Viremia; Interferon type I; Genetics; Virus; Immunology; Immune system; Innate immune system; Gene; Toll-like receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001079067,0.00007773397,0.0001004918,0.00001427685,0.00005429518,0.00001916107,0.00005049586,0.00004887575,0.0005926366],"category_scores_gemma":[0.00009761092,0.00003143426,0.00002163841,0.0001376214,0.00002468884,0.000123057,0.00005536529,0.0000642871,0.0002403158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001403297,"about_ca_system_score_gemma":0.000001075415,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001434269,"about_ca_topic_score_gemma":0.0003292096,"domain_scores_codex":[0.9993753,0.00007005531,0.0001181849,0.0002253744,0.00005081168,0.0001603144],"domain_scores_gemma":[0.9998322,0.00002951004,0.00003381572,0.00003166293,0.00002728769,0.00004555295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00009779899,0.0001376078,0.4741882,0.00001973796,0.00001701389,0.000002435335,0.00005809778,0.000002348113,0.473775,0.0004215971,0.003752057,0.04752805],"study_design_scores_gemma":[0.00003152972,0.0003168552,0.9972128,0.00001371043,0.00001323721,4.627796e-7,0.000207458,0.0002488255,0.0001356191,0.0009487889,0.000785274,0.00008539],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971367,0.00009491493,0.000002071652,0.001301544,0.000107834,0.00021959,0.000002462889,0.00004310907,0.001091752],"genre_scores_gemma":[0.9991087,0.00007596588,0.00002040349,0.0002430922,0.0001651796,0.00002551227,0.00003081289,7.1495e-7,0.000329652],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5230246,"threshold_uncertainty_score":0.6488955,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03487088406783311,"score_gpt":0.2100031655930275,"score_spread":0.1751322815251944,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}