{"id":"W2004963012","doi":"10.1016/j.tim.2014.12.008","title":"HIV-1 adaptation to HLA: a window into virus–host immune interactions","year":2015,"lang":"en","type":"review","venue":"Trends in Microbiology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":89,"is_retracted":false,"has_abstract":false,"ca_institutions":"AIDS Vancouver; Simon Fraser University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Host (biology); Immune system; Adaptation (eye); Virology; Human leukocyte antigen; Virus; Window (computing); Human immunodeficiency virus (HIV); Window of opportunity; Immunology; Genetics; Antigen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0004838759,0.0007077432,0.002249294,0.001909365,0.0001562062,0.00002511182,0.0006714802,0.0008791366,0.002567336],"category_scores_gemma":[0.0001105511,0.0005726056,0.0004870385,0.0009945708,0.000279274,0.00008540629,0.0003987091,0.001253708,0.03067137],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008707556,"about_ca_system_score_gemma":0.000415728,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009242327,"about_ca_topic_score_gemma":0.002518707,"domain_scores_codex":[0.9958447,0.001196584,0.001066851,0.0009205725,0.00003164565,0.0009396559],"domain_scores_gemma":[0.998422,0.0003052013,0.0003132704,0.0007415565,0.0001158744,0.0001021242],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001351201,0.0004149629,0.000009801744,0.0003378226,0.000713826,0.00006552198,0.001018776,0.000002311516,0.007356334,0.00004392057,0.02354938,0.9663522],"study_design_scores_gemma":[0.001155005,0.0003920816,0.00002667345,0.001176826,0.0002531423,0.0004933488,0.0001261536,1.521712e-7,0.0001608078,0.00001085953,0.9957434,0.0004615558],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001447974,0.9940656,0.00004113598,0.000222129,0.001221789,0.0007231245,0.001816714,0.00008812892,0.001676623],"genre_scores_gemma":[0.0006240995,0.9531435,0.0004492485,0.00007039413,0.0001037819,0.0007787852,0.02316122,0.00009223905,0.0215767],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.972194,"threshold_uncertainty_score":0.9996725,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06809979622688828,"score_gpt":0.37881388351809,"score_spread":0.3107140872912018,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}