{"id":"W2004986240","doi":"10.1006/viro.2000.0780","title":"A Luciferase-Reporter Gene-Expressing T-Cell Line Facilitates Neutralization and Drug-Sensitivity Assays That Use Either R5 or X4 Strains of Human Immunodeficiency Virus Type 1","year":2001,"lang":"en","type":"article","venue":"Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":57,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute; York University","keywords":"Luciferase; Biology; Tropism; Cell culture; Virology; Transfection; CXCR4; Neutralization; Reporter gene; Extracellular; Molecular biology; Gene expression; Virus; Green fluorescent protein; Gene; Cell biology; Immunology; Immune system; Chemokine; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009691405,0.001539736,0.000961392,0.0008730266,0.0006102674,0.001136205,0.001361149,0.001112738,0.004279129],"category_scores_gemma":[0.0006187243,0.000717205,0.0009129929,0.0008120404,0.0006524393,0.0008467412,0.0006037358,0.002963863,0.004033495],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006410534,"about_ca_system_score_gemma":0.0004049296,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007733997,"about_ca_topic_score_gemma":0.00105777,"domain_scores_codex":[0.9987823,0.0003352955,0.0001505367,0.0002058264,0.0003120487,0.0002139497],"domain_scores_gemma":[0.999182,0.0003096055,0.0001308825,0.0002143773,0.00007431566,0.00008875727],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001676496,0.0001249421,0.0001587138,0.00003859591,0.000008535681,0.00003487418,0.00003153114,0.00006715678,0.9972626,0.0004739273,0.000314421,0.001317034],"study_design_scores_gemma":[0.00002792358,0.0001301491,0.0004228228,0.000003717974,0.00001408463,0.0001674686,0.00001001602,0.0006906162,0.9959543,0.00004178491,0.002529105,0.000008007399],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8079327,0.001574552,0.1659483,0.0006812945,0.0004304104,0.0007419559,0.006804565,0.004923716,0.01096241],"genre_scores_gemma":[0.8404894,0.00149165,0.1227648,0.0003256597,0.0001338927,0.0008316282,0.01788767,0.0008811234,0.01519416],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004279129,"threshold_uncertainty_score":0.01431513,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05256797889448524,"score_gpt":0.2945405921800741,"score_spread":0.2419726132855888,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}