{"id":"W2005009468","doi":"10.1089/ten.tea.2012.0215","title":"Culture of Primary Bovine Chondrocytes on a Continuously Expanding Surface Inhibits Dedifferentiation","year":2012,"lang":"en","type":"article","venue":"Tissue Engineering Part A","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Aggrecan; Chondrocyte; Cell biology; Chondrogenesis; Cell culture; Chemistry; Extracellular matrix; Glycosaminoglycan; CD44; Type I collagen; Type II collagen; In vitro; Cartilage; Molecular biology; Mesenchymal stem cell; Biology; Anatomy; Pathology; Biochemistry; Medicine; Osteoarthritis; Endocrinology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006374392,0.000161615,0.0003049786,0.000061584,0.00002497771,0.000007085658,0.00003054481,0.00008663201,0.00007126031],"category_scores_gemma":[0.00003737803,0.0001417556,0.00005106073,0.0001017497,0.000008465292,0.0001002459,0.00001746796,0.0001083069,0.00005054612],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005990659,"about_ca_system_score_gemma":0.00001140517,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002628637,"about_ca_topic_score_gemma":6.315131e-7,"domain_scores_codex":[0.9992331,0.000008722353,0.000183977,0.0001252439,0.0001856606,0.0002633373],"domain_scores_gemma":[0.9996119,0.00002679554,0.00005678305,0.0001470941,0.00003104162,0.0001263704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001087295,0.0002636431,0.004443719,0.0002449027,0.00005451492,0.00001506081,0.001903658,0.0000530697,0.9874154,0.0004697611,0.0006584018,0.004369158],"study_design_scores_gemma":[0.002236465,0.001357232,0.004248219,0.0006540758,0.000115122,0.00005803198,0.00006116323,0.00004320262,0.9783803,0.000002983032,0.01265634,0.0001868846],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953131,0.002310864,0.0003853484,0.00002910002,0.0004796167,0.0003423153,0.000009144106,0.0001344147,0.0009960975],"genre_scores_gemma":[0.9946123,0.00004145679,0.002034276,0.00001902207,0.0003285209,0.0000161038,0.0001112236,0.00003038818,0.002806645],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01199794,"threshold_uncertainty_score":0.5780627,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01360489290396417,"score_gpt":0.240982930612946,"score_spread":0.2273780377089818,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}