{"id":"W2005009468","doi":"10.1089/ten.tea.2012.0215","title":"Culture of Primary Bovine Chondrocytes on a Continuously Expanding Surface Inhibits Dedifferentiation","year":2012,"lang":"en","type":"article","venue":"Tissue Engineering Part A","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Aggrecan; Chondrocyte; Cell biology; Chondrogenesis; Cell culture; Chemistry; Extracellular matrix; Glycosaminoglycan; CD44; Type I collagen; Type II collagen; In vitro; Cartilage; Molecular biology; Mesenchymal stem cell; Biology; Anatomy; Pathology; Biochemistry; Medicine; Osteoarthritis; Endocrinology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003096077,0.0003896039,0.0004260001,0.0002334399,0.0001733753,0.0003868074,0.0002609421,0.0003139021,0.001162579],"category_scores_gemma":[0.0002108547,0.0001610324,0.0004230611,0.0001984917,0.0001965695,0.0001687393,0.0003251632,0.0004228741,0.0005774524],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001783667,"about_ca_system_score_gemma":0.0002279613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009535018,"about_ca_topic_score_gemma":0.001681476,"domain_scores_codex":[0.99968,0.00003755269,0.00005319659,0.00005511308,0.000117692,0.00005647125],"domain_scores_gemma":[0.9997081,0.00009120257,0.00005267247,0.00005503621,0.00005621153,0.00003665744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002373613,0.00001350435,0.00007067564,0.00002177207,9.60646e-7,0.00001898132,0.00001034172,0.00002783068,0.9989542,0.00001040365,0.0000122598,0.0008354505],"study_design_scores_gemma":[0.000009690132,0.0005893348,0.003540559,0.00001321741,0.00001291159,0.0001656418,0.00002248962,0.0008418203,0.9924817,0.00000931898,0.002308493,0.000004872606],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9807705,0.005153012,0.0106047,0.00008460318,0.00007121598,0.0000898,0.0002708358,0.0001215315,0.002833879],"genre_scores_gemma":[0.9742366,0.002713142,0.01696783,0.00008119241,0.00004712847,0.00009504302,0.00108061,0.00004785777,0.004730558],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001162579,"threshold_uncertainty_score":0.003889263,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01360489290396417,"score_gpt":0.240982930612946,"score_spread":0.2273780377089818,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}