{"id":"W2005046011","doi":"10.1074/jbc.m708274200","title":"Functional Characterization of Escherichia coli MsbA","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":104,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Escherichia coli; Chemistry; Biology; Computational biology; Microbiology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001039422,0.0000729161,0.0002660775,0.00001545779,0.00002777984,0.000001346286,0.00005138551,0.0001324662,0.0006142721],"category_scores_gemma":[0.00003801923,0.00004523322,0.0001484817,0.00008547166,0.00009160093,0.00002662556,0.000005874389,0.0001787478,0.000002327157],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001977867,"about_ca_system_score_gemma":0.00008576141,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":1.837982e-7,"about_ca_topic_score_gemma":1.227892e-8,"domain_scores_codex":[0.9993027,0.000007368695,0.0003502555,0.000070217,0.0001824501,0.00008703178],"domain_scores_gemma":[0.9993953,0.00001418248,0.0002621235,0.00006120835,0.0001767435,0.00009045935],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004461017,0.0001747529,0.01735952,0.00004534303,0.00003507707,0.00008610084,0.0000153004,7.245273e-7,0.9816393,0.000009042565,0.00008387592,0.000104908],"study_design_scores_gemma":[0.0006078212,0.0001396385,0.2597707,0.00004854897,0.00002387928,0.0002658814,0.00002051457,0.000003994491,0.7373688,0.00003043752,0.001675673,0.00004414342],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99766,0.00009583052,0.001022858,0.0002263354,0.0001009915,0.00003191361,0.000005618659,0.000007423086,0.000848981],"genre_scores_gemma":[0.9979123,0.0002749009,0.0005613366,0.00009781749,0.0003115768,7.037913e-7,0.00003309671,0.000004192977,0.0008040231],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2442705,"threshold_uncertainty_score":0.6725848,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02904228955293671,"score_gpt":0.2288928240759937,"score_spread":0.199850534523057,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}