{"id":"W2005046011","doi":"10.1074/jbc.m708274200","title":"Functional Characterization of Escherichia coli MsbA","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":104,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Escherichia coli; Chemistry; Biology; Computational biology; Microbiology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000273531,0.0004829864,0.0003630215,0.0004220474,0.0002169299,0.0005373202,0.0002785351,0.0003663731,0.001260786],"category_scores_gemma":[0.0005432467,0.0001318561,0.0003121771,0.0005533822,0.0002003542,0.0003062431,0.0002330843,0.0006185569,0.001105341],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004909997,"about_ca_system_score_gemma":0.0003197128,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003532734,"about_ca_topic_score_gemma":0.001617417,"domain_scores_codex":[0.9996518,0.00006964013,0.00002911733,0.00004222401,0.0001436391,0.00006367978],"domain_scores_gemma":[0.9995645,0.00008131718,0.0000511957,0.00004802896,0.0001857879,0.00006920149],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002103697,0.00002657639,0.0001154332,0.00002237822,0.00000217801,0.00002083214,0.00001455727,0.00003809755,0.9988287,0.00005372666,0.0000320033,0.0008245512],"study_design_scores_gemma":[0.000003686662,0.00009436436,0.003187813,0.000006754946,0.000006288621,0.0001565539,0.00005481155,0.0005381716,0.9911396,0.00003517459,0.004770888,0.000005968927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9718759,0.002367632,0.01667287,0.0007196097,0.00008474474,0.0001647589,0.002853332,0.000211848,0.005049233],"genre_scores_gemma":[0.9667671,0.001370188,0.01406601,0.000280719,0.00002242904,0.0001088566,0.006524091,0.0001487221,0.01071179],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003532734,"threshold_uncertainty_score":0.007024348,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02904228955293671,"score_gpt":0.2288928240759937,"score_spread":0.199850534523057,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}