{"id":"W2005051689","doi":"10.1016/j.ahj.2012.04.007","title":"Pexelizumab fails to inhibit assembly of the terminal complement complex in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention. Insight from a substudy of the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX-AMI) trial","year":2012,"lang":"en","type":"article","venue":"American Heart Journal","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":42,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; Université de Montréal; Montreal Heart Institute","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Natriuretic peptide; Myocardial infarction; Percutaneous coronary intervention; Chemokine; Internal medicine; Placebo; Complement system; Cardiology; Inflammation; Immunology; Gastroenterology; Heart failure; Antibody; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001103214,0.0004229574,0.001402446,0.0001031572,0.0001937631,0.0006807087,0.0003286027,0.0005622293,0.001943702],"category_scores_gemma":[0.001918689,0.0001663224,0.0007969189,0.0002228836,0.0002311339,0.0004274058,0.0001784574,0.001451339,0.000307575],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003690567,"about_ca_system_score_gemma":0.0002912603,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005781082,"about_ca_topic_score_gemma":0.001800191,"domain_scores_codex":[0.9996061,0.0001846467,0.00003167065,0.00004496922,0.00006525361,0.00006729711],"domain_scores_gemma":[0.9992399,0.0003041564,0.0001857766,0.00006807766,0.00006300101,0.0001390426],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.4698884,0.004822765,0.1196274,0.001956303,0.01332202,0.000891424,0.0002965747,0.001222494,0.03765772,0.001209431,0.01390538,0.3352001],"study_design_scores_gemma":[0.1699604,0.08579819,0.7014954,0.0005032265,0.0134085,0.001667805,0.0002371087,0.002196268,0.006710704,0.001446235,0.01650096,0.00007502505],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.97569,0.0185672,0.0001809485,0.001262371,0.0001869281,0.0001384494,0.0004045688,0.00002424787,0.003545228],"genre_scores_gemma":[0.9951231,0.002948812,0.0001327675,0.0006513541,0.000185901,0.00005195276,0.0004335403,0.000003766864,0.0004687688],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001943702,"threshold_uncertainty_score":0.00650233,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01732720539405855,"score_gpt":0.2862372745684031,"score_spread":0.2689100691743446,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}