{"id":"W2005062632","doi":"10.1016/j.stem.2010.12.009","title":"ΔNp63α Is an Oncogene that Targets Chromatin Remodeler Lsh to Drive Skin Stem Cell Proliferation and Tumorigenesis","year":2011,"lang":"en","type":"article","venue":"Cell stem cell","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":192,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"National Cancer Institute","keywords":"Biology; Carcinogenesis; Chromatin; Stem cell; Cell biology; Oncogene; Cell; Cancer research; Genetics; Gene; Cell cycle","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002002799,0.0003644427,0.0002848957,0.00006749651,0.0001688202,0.00007012021,0.0003217775,0.0002662,0.00005927325],"category_scores_gemma":[7.020109e-7,0.0003646602,0.00009784961,0.0000893016,0.00004042965,0.00001387399,0.0002068117,0.0000945042,0.00006661411],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004541611,"about_ca_system_score_gemma":0.00009106637,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000612089,"about_ca_topic_score_gemma":0.00008066022,"domain_scores_codex":[0.9981529,0.00009087218,0.0003625577,0.0007711463,0.0001886321,0.0004339418],"domain_scores_gemma":[0.9987149,0.000006861567,0.0002053007,0.0006596898,0.0001132438,0.0003000128],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006422378,0.0002580165,0.001471248,0.0001625401,0.00001984914,0.000007343263,0.003443081,0.0001333522,0.9903572,0.000006810264,0.001162417,0.00291391],"study_design_scores_gemma":[0.0005596888,0.0005693085,0.0008546324,0.00001166436,0.00003979935,0.000008710213,0.00098616,0.002321459,0.9904097,0.00002853261,0.00372459,0.0004857481],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988868,0.000917884,0.002528305,0.00001858863,0.0001871745,0.0006069336,0.0000678952,0.00002578735,0.006779427],"genre_scores_gemma":[0.988252,0.0003143827,0.004758222,0.0003341472,0.0001553432,0.00005120043,0.0001384296,0.00008215071,0.005914063],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002562173,"threshold_uncertainty_score":0.9998806,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01527169784255332,"score_gpt":0.2004745971007562,"score_spread":0.1852028992582029,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}