{"id":"W2005135029","doi":"10.1016/s0006-2952(01)00774-2","title":"Molecular cloning and functional characterization of murine cysteinyl-leukotriene 1 (CysLT1) receptors11Abbreviations: LT, leukotriene; hCysLT1R, human cysteinyl-leukotriene receptor (subtype 1); mCysLT1R, mouse cysteinyl-leukotriene receptor (subtype 1); CysLT2R, cysteinyl-leukotriene receptor (subtype 2); HEK, human embryonic kidney; ORF, open reading frame; RT-PCR, reverse transcription-polymerase chain reaction; and RACE, rapid amplification of cDNA ends.","year":2001,"lang":"en","type":"article","venue":"Biochemical Pharmacology","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"National Heart, Lung, and Blood Institute; Philippe Foundation","keywords":"Leukotriene D4; Receptor; Molecular biology; Chemistry; Leukotriene; Amino acid; HEK 293 cells; Leukotriene C4; Biochemistry; Biology; Antagonist","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.002150366,0.002000527,0.003344621,0.001818781,0.001296285,0.0002164226,0.001153636,0.001799134,0.002759729],"category_scores_gemma":[0.001387383,0.002093072,0.0007824334,0.003220928,0.001632265,0.00150041,0.0007180938,0.001712699,0.0001312431],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001278257,"about_ca_system_score_gemma":0.001520579,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000372108,"about_ca_topic_score_gemma":0.000009611757,"domain_scores_codex":[0.987349,0.001458115,0.00419984,0.003284677,0.001753648,0.001954718],"domain_scores_gemma":[0.9900075,0.0005296938,0.003386086,0.001838653,0.002006746,0.00223128],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007523886,0.002061458,0.001789219,0.001341705,0.0009221146,0.00007175281,0.0006616054,0.00003073251,0.9596102,0.0007842051,0.02344151,0.001761605],"study_design_scores_gemma":[0.01670278,0.002982102,0.002187525,0.001170316,0.001513996,0.0002876247,0.0004840641,0.0002719367,0.8581385,0.00006180589,0.1142623,0.001937024],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9804615,0.00752497,0.001146024,0.002102733,0.001921447,0.004788261,0.001052355,0.0005092617,0.0004934467],"genre_scores_gemma":[0.9740057,0.00616119,0.001558932,0.001635476,0.00181131,0.0009865513,0.009216882,0.0004749091,0.004149049],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1014717,"threshold_uncertainty_score":0.9994968,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01995347673607244,"score_gpt":0.2837141640114944,"score_spread":0.2637606872754219,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}