{"id":"W2005141685","doi":"10.1016/j.ab.2010.04.017","title":"Sodium dodecyl sulfate–polyacrylamide gel electrophoresis for screening nonaggregating human antibody heavy chain variable domains","year":2010,"lang":"en","type":"article","venue":"Analytical Biochemistry","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"National Research Council Canada; Institute for Biological Sciences","funders":"","keywords":"Sodium dodecyl sulfate; Polyacrylamide gel electrophoresis; Gel electrophoresis; Chemistry; Chromatography; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006098525,0.0003726966,0.0005933981,0.0001183569,0.0005031317,0.00009816253,0.0003419742,0.0003763594,0.0004441543],"category_scores_gemma":[0.0006615838,0.0003192778,0.0003628765,0.0004245291,0.0004071308,0.00006004759,0.0001735723,0.0009963755,0.00003269276],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005952489,"about_ca_system_score_gemma":0.0002404767,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003085806,"about_ca_topic_score_gemma":0.00001540108,"domain_scores_codex":[0.9969764,0.00002514339,0.0005434158,0.0007255034,0.0006288096,0.00110078],"domain_scores_gemma":[0.9980292,0.000363446,0.0001161284,0.0005738421,0.0002951945,0.0006222332],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006297724,0.0002490539,0.006516015,0.0003669396,0.0002307282,0.0000690517,0.00001434223,9.454403e-7,0.9835128,0.005222219,0.0021072,0.001080937],"study_design_scores_gemma":[0.002358773,0.0004146331,0.00318766,0.0002206565,0.0002668753,0.0002108981,0.00008308107,0.01090036,0.9667671,0.001471042,0.01350746,0.0006114523],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9826859,0.0002358248,0.002065304,0.002970322,0.00007410167,0.0003852733,0.00009280014,0.00009967939,0.01139074],"genre_scores_gemma":[0.96962,0.00004410626,0.01392135,0.0005688718,0.001387582,0.00004253797,0.0006528659,0.00006319342,0.01369946],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01674569,"threshold_uncertainty_score":0.9999259,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01653051398535747,"score_gpt":0.338021933575081,"score_spread":0.3214914195897235,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}