{"id":"W2005259727","doi":"10.1016/j.cardiores.2005.04.028","title":"Reduced endothelial secretion and plasma levels of transforming growth factor-β1 in patients with hereditary hemorrhagic telangiectasia type 1","year":2005,"lang":"en","type":"article","venue":"Cardiovascular Research","topic":"Vascular Anomalies and Treatments","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of Saskatchewan; University of Toronto; SickKids Foundation; Hospital for Sick Children; Heart and Stroke Foundation","funders":"Wellcome Trust; Heart and Stroke Foundation of Canada; March of Dimes Foundation","keywords":"Endoglin; SMAD; Transforming growth factor; ACVRL1; Internal medicine; Endocrinology; Receptor; Telangiectasia; Transforming growth factor beta; Chemistry; Medicine; Biology; Pathology; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001080791,0.0002955756,0.0002630015,0.000696945,0.0002084209,0.0003009478,0.0001069187,0.0002800216,0.001651084],"category_scores_gemma":[0.0007090998,0.0001422348,0.0001385325,0.0004487543,0.0001684024,0.0001673306,0.00009164532,0.0002259726,0.0001661696],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000141374,"about_ca_system_score_gemma":0.00007028221,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005442636,"about_ca_topic_score_gemma":0.0003765621,"domain_scores_codex":[0.9998907,0.00002049662,0.00001724925,0.00003647629,0.0000223993,0.00001265695],"domain_scores_gemma":[0.9996858,0.00006744821,0.0001713853,0.00001341086,0.00002324827,0.00003882308],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001361844,0.0001097549,0.9452306,0.0000600719,0.0001393147,0.00342269,0.000280183,0.0001530445,0.03901937,0.00006272522,0.0001813822,0.00997893],"study_design_scores_gemma":[0.00002693248,0.0004232787,0.9822113,0.000008462229,0.00009085276,0.01244989,0.0001275958,0.0003394419,0.003977564,0.00005157505,0.0002873233,0.000005807253],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994556,0.0002030553,0.0001059365,0.00001359441,0.000001924402,0.0000014144,0.00007133881,0.00000752913,0.0001396006],"genre_scores_gemma":[0.9995434,0.00009385138,0.0001152364,0.00001074444,0.000007325821,0.000002643493,0.0001046801,0.000002023099,0.0001200954],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001651084,"threshold_uncertainty_score":0.005523384,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03663667911971109,"score_gpt":0.2878509325904726,"score_spread":0.2512142534707615,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}