{"id":"W2005259727","doi":"10.1016/j.cardiores.2005.04.028","title":"Reduced endothelial secretion and plasma levels of transforming growth factor-β1 in patients with hereditary hemorrhagic telangiectasia type 1","year":2005,"lang":"en","type":"article","venue":"Cardiovascular Research","topic":"Vascular Anomalies and Treatments","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of Saskatchewan; University of Toronto; SickKids Foundation; Hospital for Sick Children; Heart and Stroke Foundation","funders":"Wellcome Trust; Heart and Stroke Foundation of Canada; March of Dimes Foundation","keywords":"Endoglin; SMAD; Transforming growth factor; ACVRL1; Internal medicine; Endocrinology; Receptor; Telangiectasia; Transforming growth factor beta; Chemistry; Medicine; Biology; Pathology; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004933453,0.0001571881,0.0004641308,0.0002731239,0.00007044826,0.0000135702,0.00007652812,0.0001087556,0.00004900491],"category_scores_gemma":[0.00007997898,0.000120325,0.000247421,0.00040611,0.000117023,0.0001307681,0.00003581206,0.0002868398,0.00001471899],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001495674,"about_ca_system_score_gemma":0.0001158121,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001680722,"about_ca_topic_score_gemma":0.00002013711,"domain_scores_codex":[0.9979387,0.0001560955,0.0002088657,0.0003393096,0.0009757254,0.0003813239],"domain_scores_gemma":[0.999117,0.00004210692,0.0000204818,0.0003625939,0.0003211563,0.0001367151],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004648568,0.001388046,0.614994,0.001413271,0.008212965,0.0009779625,0.003507949,0.0001653929,0.00612636,0.0001397531,0.00006201562,0.3583637],"study_design_scores_gemma":[0.01582159,0.001546329,0.9555301,0.0003200459,0.0003346844,0.0001972272,0.0003448742,0.0001596708,0.02443878,0.00002127739,0.001023459,0.0002619378],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959548,0.001958612,0.0000271317,0.00006046707,0.00003775517,0.0008052882,0.00004127617,0.00001729117,0.001097369],"genre_scores_gemma":[0.9991457,0.0001510038,0.0004097724,0.000006403634,0.0001072513,0.00001947031,0.00005505247,0.00003547778,0.00006985814],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3581018,"threshold_uncertainty_score":0.4906713,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03663667911971109,"score_gpt":0.2878509325904726,"score_spread":0.2512142534707615,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}