{"id":"W2005290451","doi":"10.2478/s13380-011-0042-1","title":"The cellular prion protein in multiple sclerosis: A potential target for neurotherapeutics?","year":2011,"lang":"en","type":"article","venue":"Translational Neuroscience","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Multiple sclerosis; Neuroprotection; Disease; Neuroscience; Pathogenesis; Biology; Neurodegeneration; Neurotrophin; Immunology; Medicine; Pathology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001969759,0.00008829567,0.00005029989,0.00002379239,0.0002316413,0.00003119223,0.0002507012,0.00004111133,0.000005885692],"category_scores_gemma":[0.00005417586,0.00007214785,0.00007001807,0.00009464922,0.0001118805,0.000009476474,0.00002020964,0.00005142669,0.000001123859],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002602327,"about_ca_system_score_gemma":0.00006356435,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000607859,"about_ca_topic_score_gemma":0.00001025282,"domain_scores_codex":[0.9991599,0.00005027426,0.0001527615,0.0002837045,0.000140672,0.0002127028],"domain_scores_gemma":[0.99971,0.00001258491,0.00004342413,0.0001530163,0.00003311866,0.00004786951],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002128664,0.00004740843,0.0009206595,0.000005625421,0.000001342148,7.757831e-7,0.00002691699,0.0002092518,0.9912237,0.0004129309,0.000006609597,0.006931907],"study_design_scores_gemma":[0.001603945,0.0005054011,0.06070096,0.00002525436,0.000008908069,0.000003276795,0.00001676324,0.01862748,0.8845598,0.004079008,0.02955403,0.0003152216],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9288139,0.00155722,0.06787302,0.0004233781,0.0001775451,0.001056194,0.00003494553,0.00001365444,0.00005010954],"genre_scores_gemma":[0.9972835,0.0001281027,0.002118554,0.0002186552,0.00005034334,0.0001359281,0.000008971867,0.00001185417,0.00004410015],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1066639,"threshold_uncertainty_score":0.2942104,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06336759843565398,"score_gpt":0.2422259364624526,"score_spread":0.1788583380267986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}