{"id":"W2005328285","doi":"10.2165/00003088-200038010-00003","title":"Pharmacokinetic-Pharmacodynamic Consequences and Clinical Relevance of Cytochrome P450 3A4 Inhibition","year":2000,"lang":"en","type":"review","venue":"Clinical Pharmacokinetics","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":907,"is_retracted":false,"has_abstract":false,"ca_institutions":"London Health Sciences Centre; Western University","funders":"","keywords":"Pharmacology; Drug interaction; Ritonavir; CYP3A4; Ketoconazole; Triazolam; Pharmacokinetics; Dextromethorphan; Medicine; Chemistry; Benzodiazepine; Cytochrome P450; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2913135195647739,"score_gpt":0.5702358397399223,"score_spread":0.2789223201751484,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}