{"id":"W2005363404","doi":"10.1097/mib.0b013e3182807600","title":"Epithelial Cell Extrusion Leads to Breaches in the Intestinal Epithelium","year":2013,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"Barrier Structure and Function Studies","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Epithelium; Intestinal epithelium; Caco-2; Extrusion; Intestinal permeability; Nigericin; Caspase 3; Molecular biology; Chemistry; Apoptosis; Cell biology; Biology; In vitro; Pathology; Immunology; Materials science; Programmed cell death; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001146259,0.0002297683,0.0001626637,0.0001357414,0.0002722786,0.0001367919,0.0004573415,0.0000482229,0.0004039424],"category_scores_gemma":[0.0004479127,0.0001502705,0.00009343226,0.0002593313,0.0001912357,0.0003023773,0.0001600159,0.0001906363,0.001016488],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002944083,"about_ca_system_score_gemma":0.00005088899,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005233153,"about_ca_topic_score_gemma":0.00002480309,"domain_scores_codex":[0.9983374,0.0002123027,0.0003001034,0.0004122573,0.0003723193,0.0003656407],"domain_scores_gemma":[0.9989356,0.0003752643,0.00007726942,0.0003968286,0.00005086547,0.000164149],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003821623,0.0003851608,0.344595,0.0001698016,0.000009444891,0.0003075756,0.008723854,0.0002260447,0.5880405,0.001939915,0.02831731,0.02690328],"study_design_scores_gemma":[0.0004308799,0.00008682463,0.9594444,0.00002841637,0.0000203565,0.00002392357,0.0008444963,0.00005954598,0.02820306,0.001712111,0.008839009,0.0003069685],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933428,0.0001232249,0.00006875768,0.0009801504,0.0004473003,0.0005203127,0.00003384832,0.0001140906,0.004369485],"genre_scores_gemma":[0.9954525,0.00001613462,0.0000439498,0.003550517,0.0003009144,0.0002339855,0.000001648388,0.00001934587,0.0003809598],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6148494,"threshold_uncertainty_score":0.9997613,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01702818148926551,"score_gpt":0.2347038963287329,"score_spread":0.2176757148394674,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}