{"id":"W2005370465","doi":"10.1016/j.bbagrm.2014.05.015","title":"Fluorescence tools to investigate riboswitch structural dynamics","year":2014,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"Engineering and Physical Sciences Research Council","keywords":"Riboswitch; Förster resonance energy transfer; Aptamer; Context (archaeology); Folding (DSP implementation); Computational biology; Single-molecule FRET; Chemistry; Biophysics; Fluorescence; Nanotechnology; Biology; RNA; Biochemistry; Non-coding RNA; Physics; Gene; Genetics; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0008475101,0.001894487,0.002683968,0.0003626366,0.000375582,0.0003367818,0.002323703,0.001625406,0.00003902748],"category_scores_gemma":[0.0001829866,0.00170554,0.001444291,0.000606394,0.0002360759,0.00003084889,0.001128762,0.0005873388,0.0002377993],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002226313,"about_ca_system_score_gemma":0.0007378845,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000134086,"about_ca_topic_score_gemma":0.00001049949,"domain_scores_codex":[0.9929757,0.0008817508,0.001452021,0.002529079,0.0008626718,0.001298801],"domain_scores_gemma":[0.994699,0.00009130865,0.001112496,0.003029157,0.0001994027,0.0008686409],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004488134,0.00004085269,7.191855e-9,0.001267193,0.0003250081,0.000006903987,0.00002225706,0.000002042931,0.7655535,0.002967632,0.0004512513,0.2293185],"study_design_scores_gemma":[0.000282137,0.0006124252,0.000005450148,0.002168654,0.0006655427,0.0000928786,0.00001262277,0.00005116434,0.9345855,0.001933641,0.05747845,0.002111498],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1764955,0.7852867,0.01694558,0.0008625105,0.00505245,0.01054605,0.003402374,0.0007273642,0.0006814894],"genre_scores_gemma":[0.03628842,0.9194972,0.03200669,0.001279104,0.002379397,0.001063557,0.005172959,0.0009979268,0.001314748],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.227207,"threshold_uncertainty_score":0.9996707,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02638585288766765,"score_gpt":0.286738967643773,"score_spread":0.2603531147561054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}