{"id":"W2005373529","doi":"10.1016/j.jmb.2009.07.026","title":"Crystal Structures of Wzb of Escherichia coli and CpsB of Streptococcus pneumoniae, Representatives of Two Families of Tyrosine Phosphatases that Regulate Capsule Assembly","year":2009,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Canada Research Chairs; Wellcome Trust","keywords":"Protein tyrosine phosphatase; Phosphatase; Biology; Biochemistry; Escherichia coli; Tyrosine; Active site; Dual-specificity phosphatase; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000206807,0.000826469,0.0009814557,0.0003684092,0.0007083862,0.0008730045,0.001022484,0.001074547,0.003198213],"category_scores_gemma":[0.000548474,0.0005664658,0.0003645093,0.0009784143,0.0003242033,0.0004931241,0.0003838567,0.001919851,0.0008162328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001321226,"about_ca_system_score_gemma":0.001022226,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005642486,"about_ca_topic_score_gemma":0.005337912,"domain_scores_codex":[0.999797,0.00002443247,0.000008085254,0.00003366794,0.00009782959,0.00003893486],"domain_scores_gemma":[0.9997748,0.00004601856,0.00004350788,0.00000974257,0.00004372743,0.00008224587],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003358898,0.001620835,0.0138107,0.001952521,0.0004936745,0.002982468,0.00115066,0.01518455,0.8630899,0.01473123,0.03773832,0.04388621],"study_design_scores_gemma":[0.002898916,0.001127857,0.1145839,0.0003270621,0.0005603327,0.004571299,0.001554834,0.208243,0.4178394,0.00563312,0.2422834,0.0003769053],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9521945,0.01228712,0.01188228,0.00185181,0.000263133,0.0001606798,0.01078375,0.0007227462,0.009854028],"genre_scores_gemma":[0.8954914,0.006849182,0.03548473,0.0005613446,0.00004827672,0.0003144513,0.04982271,0.0003498418,0.01107806],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005642486,"threshold_uncertainty_score":0.01121926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009246953384570883,"score_gpt":0.2899340537073121,"score_spread":0.2806871003227412,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}