{"id":"W2005378502","doi":"10.1139/o05-044","title":"DNA break repair: refined rules of an already complicated game","year":2005,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"PARP inhibition in cancer therapy","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Deutsche Forschungsgemeinschaft; Deutscher Akademischer Austauschdienst","keywords":"Poly ADP ribose polymerase; Polymerase; DNA repair; DNA; DNA damage; Computational biology; DNA polymerase; Computer science; Biology; Cell biology; Genetics; Chemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009133931,0.000788967,0.001340084,0.001217831,0.0005777709,0.002144442,0.001237227,0.001636383,0.002414698],"category_scores_gemma":[0.00089022,0.0003110603,0.0002946013,0.001210564,0.00283268,0.004181148,0.0009893464,0.002443859,0.00240285],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001510316,"about_ca_system_score_gemma":0.001092874,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009801114,"about_ca_topic_score_gemma":0.001093668,"domain_scores_codex":[0.9996257,0.00008637468,0.00003640381,0.00007659046,0.0001541363,0.00002085216],"domain_scores_gemma":[0.9996282,0.000211593,0.00002538441,0.00003018542,0.00007509708,0.00002952531],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007218747,0.00005765273,0.000183767,0.005002013,0.0000780409,0.0003634176,0.000592344,0.005220017,0.004521126,0.2656424,0.03400227,0.6842647],"study_design_scores_gemma":[0.00001171425,0.0000530362,0.0002076576,0.0009754376,0.00001734822,0.000573103,0.0001932109,0.0008141455,0.0007033875,0.1588383,0.8375833,0.00002923573],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001023589,0.9641862,0.01322869,0.004244489,0.0007283804,0.00001961124,0.00003769766,0.00006406359,0.0164673],"genre_scores_gemma":[0.00900935,0.9772267,0.004861556,0.001318678,0.0007314159,0.00003318083,0.00004581234,0.00001685932,0.006756432],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002414698,"threshold_uncertainty_score":0.01095819,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04708099302327313,"score_gpt":0.3568744036745696,"score_spread":0.3097934106512965,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}