{"id":"W2005397880","doi":"10.1016/j.nurt.2008.08.007","title":"Spinal Muscular Atrophy","year":2008,"lang":"en","type":"review","venue":"Neurotherapeutics","topic":"Neurogenetic and Muscular Disorders Research","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Center for Research Resources; National Institutes of Health; Georgia Clinical and Translational Science Alliance; Spinal Muscular Atrophy Foundation","keywords":"SMA*; Spinal muscular atrophy; SMN1; Clinical trial; Medicine; Disease; Bioinformatics; Neuroscience; Preclinical testing; Pathology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004125866,0.001294912,0.002289051,0.003773403,0.0004619428,0.0008097748,0.0009311975,0.001142611,0.008841887],"category_scores_gemma":[0.0007736126,0.0002898349,0.0005397237,0.0027739,0.0006783488,0.00115472,0.0009963651,0.001252128,0.004274793],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006324448,"about_ca_system_score_gemma":0.001436783,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001847787,"about_ca_topic_score_gemma":0.005325308,"domain_scores_codex":[0.9997697,0.00003473364,0.0000485601,0.00005094581,0.00006778974,0.00002822229],"domain_scores_gemma":[0.9997335,0.00008847935,0.00007648011,0.00001397082,0.00006408968,0.00002338906],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006895818,0.00004795627,0.000225707,0.01105501,0.0001095473,0.0005413813,0.00002775803,0.0001427937,0.0008874953,0.0009493734,0.04445558,0.9414885],"study_design_scores_gemma":[0.0000532788,0.0001193825,0.002147866,0.007814817,0.0004345844,0.008870431,0.00007458522,0.0000755485,0.0006196283,0.001170763,0.9785997,0.00001949877],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000139285,0.9969642,0.0001542839,0.0002335064,0.0003989215,0.000007565369,0.00003202941,0.00001350632,0.0020567],"genre_scores_gemma":[0.001564277,0.9935902,0.0003764571,0.0004820416,0.0005611932,0.00001439988,0.0001051077,0.000002918789,0.003303426],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.008841887,"threshold_uncertainty_score":0.0295791,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1412575311618893,"score_gpt":0.426179409533586,"score_spread":0.2849218783716967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}