{"id":"W2005397880","doi":"10.1016/j.nurt.2008.08.007","title":"Spinal Muscular Atrophy","year":2008,"lang":"en","type":"review","venue":"Neurotherapeutics","topic":"Neurogenetic and Muscular Disorders Research","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Center for Research Resources; National Institutes of Health; Georgia Clinical and Translational Science Alliance; Spinal Muscular Atrophy Foundation","keywords":"SMA*; Spinal muscular atrophy; SMN1; Clinical trial; Medicine; Disease; Bioinformatics; Neuroscience; Preclinical testing; Pathology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0000532298,0.0005291207,0.001589901,0.0003048284,0.0001084171,0.00002573308,0.0002985936,0.0003570303,0.0001556692],"category_scores_gemma":[0.00002676368,0.0004193798,0.00137114,0.0004927939,0.0001943347,0.0000176868,0.00005878589,0.0009510601,0.0005170343],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005624094,"about_ca_system_score_gemma":0.0006945376,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003199667,"about_ca_topic_score_gemma":3.215002e-7,"domain_scores_codex":[0.997456,0.0002077989,0.0004896443,0.0006235963,0.0006977822,0.0005252274],"domain_scores_gemma":[0.9985192,0.00004299191,0.0001257126,0.0009660145,0.00008770464,0.0002583729],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002356101,0.0001471827,0.000004824065,0.006800308,0.0002829199,0.0006302776,0.000008429458,1.055942e-7,0.000005728552,0.00003300424,0.000424901,0.9916388],"study_design_scores_gemma":[0.0005220702,0.0006921284,0.00001486662,0.00189016,0.0008314658,0.002441309,0.000001961621,0.000004599329,0.000003518398,0.000006462918,0.9933038,0.0002877103],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001242057,0.9951763,0.0001085693,0.00007154092,0.0002010379,0.001753135,0.000008988588,0.00009749352,0.002570475],"genre_scores_gemma":[0.000003737772,0.9966846,0.0002502517,0.0009141304,0.0003395933,0.0001179668,0.00003331985,0.0002403629,0.001416046],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9928789,"threshold_uncertainty_score":0.9998258,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1412575311618893,"score_gpt":0.426179409533586,"score_spread":0.2849218783716967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}