{"id":"W2005441809","doi":"10.1038/nrm2434","title":"Cytochrome c: functions beyond respiration","year":2008,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1106,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Cytochrome c; Apoptosis; Apoptosome; Mitochondrion; Cytochrome; Cell biology; Cytochrome b; Biology; Cytosol; Programmed cell death; Mitochondrial apoptosis-induced channel; Intrinsic apoptosis; Biochemistry; Caspase; Mitochondrial DNA; Gene; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009386825,0.001397082,0.00177119,0.001163293,0.0004687409,0.001651407,0.001941034,0.002307248,0.001699751],"category_scores_gemma":[0.0007667303,0.0004105798,0.0003283503,0.002313705,0.002107794,0.002441188,0.00137571,0.003828877,0.002772998],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001311081,"about_ca_system_score_gemma":0.001146347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008393551,"about_ca_topic_score_gemma":0.001383062,"domain_scores_codex":[0.9996787,0.00003812015,0.00003777411,0.00006916769,0.0001452845,0.00003094232],"domain_scores_gemma":[0.999597,0.0001223031,0.00004675134,0.00002866106,0.0001402166,0.00006502962],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001423908,0.00003936045,0.0001844893,0.006343255,0.00008164467,0.0002613103,0.00006074664,0.0004766758,0.008603849,0.01473807,0.07607447,0.8929937],"study_design_scores_gemma":[0.00002202633,0.00002616075,0.0003713582,0.0004421354,0.00003553027,0.0007720544,0.000029953,0.00008273785,0.001305345,0.005492992,0.9914057,0.0000140456],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001175482,0.9954883,0.0009040627,0.0009341472,0.001357871,0.000004466419,0.00001332521,0.00001512351,0.001165083],"genre_scores_gemma":[0.001633104,0.9935626,0.0005737311,0.0008160184,0.001436223,0.00001072051,0.00003774282,0.000003918079,0.001925861],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002307248,"threshold_uncertainty_score":0.009512603,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01762449773476279,"score_gpt":0.3074600017338097,"score_spread":0.289835503999047,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}