{"id":"W2005482433","doi":"10.1097/cad.0b013e32832cb8bc","title":"Interaction of ionizing radiation and ZRBA1, a mixed EGFR/DNA-targeting molecule","year":2009,"lang":"en","type":"article","venue":"Anti-Cancer Drugs","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Clonogenic assay; Ionizing radiation; Comet assay; Cell cycle; Cell cycle checkpoint; Apoptosis; Cancer research; Epidermal growth factor receptor; DNA damage; Tyrosine kinase; Chemistry; DNA repair; Molecular biology; Biology; Irradiation; Signal transduction; Cell biology; Receptor; DNA; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001204881,0.0003454642,0.000289253,0.0002254288,0.00009303418,0.0002051733,0.0002472312,0.0003172622,0.001666247],"category_scores_gemma":[0.0001171596,0.0001644551,0.0002576775,0.0001644217,0.00009958349,0.0001165619,0.0001470258,0.0003158085,0.000385836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002047084,"about_ca_system_score_gemma":0.0001373638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003633818,"about_ca_topic_score_gemma":0.0004235255,"domain_scores_codex":[0.9998885,0.00002203916,0.000005839384,0.00003007272,0.00002584505,0.00002762873],"domain_scores_gemma":[0.9999607,0.00001057123,0.00001256405,0.000003592479,0.000003700371,0.000008978487],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000218335,0.00005529748,0.0003024577,0.000110924,0.00003077704,0.00003992847,0.00001518894,0.0001739917,0.9952684,0.0001247251,0.00007627988,0.00358377],"study_design_scores_gemma":[0.0000386958,0.0009257815,0.002702603,0.00001011802,0.00005249896,0.0002134528,0.00001355218,0.0006211658,0.991138,0.00001657699,0.004260886,0.000006537437],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891133,0.006078206,0.002540604,0.00009595503,0.00004805203,0.00006612986,0.0001972779,0.00007464494,0.001785602],"genre_scores_gemma":[0.9929385,0.00227851,0.002341548,0.00004866973,0.00001996236,0.00004987739,0.0003555384,0.000007748568,0.001959736],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001666247,"threshold_uncertainty_score":0.005574167,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009402137015691033,"score_gpt":0.2689424285463449,"score_spread":0.2595402915306538,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}