{"id":"W2005482433","doi":"10.1097/cad.0b013e32832cb8bc","title":"Interaction of ionizing radiation and ZRBA1, a mixed EGFR/DNA-targeting molecule","year":2009,"lang":"en","type":"article","venue":"Anti-Cancer Drugs","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Clonogenic assay; Ionizing radiation; Comet assay; Cell cycle; Cell cycle checkpoint; Apoptosis; Cancer research; Epidermal growth factor receptor; DNA damage; Tyrosine kinase; Chemistry; DNA repair; Molecular biology; Biology; Irradiation; Signal transduction; Cell biology; Receptor; DNA; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001080426,0.000106073,0.0001262247,0.00003971326,0.00005786491,0.00001909921,0.0000653499,0.00007434302,0.00001266642],"category_scores_gemma":[0.000008756937,0.0001096453,0.00005414547,0.00006992931,0.00002107609,0.000008340874,0.00002532506,0.00005542755,0.000001008427],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001955625,"about_ca_system_score_gemma":0.00003728504,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006392168,"about_ca_topic_score_gemma":0.00001025962,"domain_scores_codex":[0.99934,0.00002408103,0.0001708023,0.0002266348,0.00008658849,0.0001518959],"domain_scores_gemma":[0.9996428,0.000005036372,0.0001249462,0.0001297035,0.0000574788,0.00004000651],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004087916,0.00002710561,0.0001516549,0.00001143969,0.00003145028,2.783662e-7,0.0001627476,0.00003633707,0.9464167,0.0001994782,0.0002597189,0.0526622],"study_design_scores_gemma":[0.0005049914,0.0001431358,0.001019517,0.00002670052,0.00002343649,0.000001955729,0.0001870833,0.0002954887,0.9830115,0.0001281591,0.01452656,0.000131404],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946818,0.002802046,0.001339124,0.0003263155,0.0002474973,0.0001080163,0.000009626586,0.000009896175,0.00047568],"genre_scores_gemma":[0.9958941,0.002986829,0.0002763385,0.0004611567,0.0001934651,0.00000820352,0.0000433207,0.00001263068,0.0001239554],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05253079,"threshold_uncertainty_score":0.4471204,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009402137015691033,"score_gpt":0.2689424285463449,"score_spread":0.2595402915306538,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}