{"id":"W2005489723","doi":"10.1007/s00018-004-4199-4","title":"Biological functions of the ING family tumor suppressors","year":2004,"lang":"en","type":"review","venue":"Cellular and Molecular Life Sciences","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":111,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Biology; Cell cycle; Cell biology; Histone deacetylase; Suppressor; Transcription factor; Histone; Gene; Tumor suppressor gene; Epigenetics; Cell cycle checkpoint; E2F1; HDAC11; DNA repair; Genetics; Senescence; DNA damage; Cancer research; Carcinogenesis; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005327059,0.001156741,0.001237624,0.001056629,0.0002641102,0.000949682,0.001121369,0.0008096459,0.001268618],"category_scores_gemma":[0.0003416852,0.0002121063,0.0002758445,0.001396083,0.0007431846,0.0007077249,0.0005423855,0.001687229,0.001314197],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006346342,"about_ca_system_score_gemma":0.0005457131,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000520932,"about_ca_topic_score_gemma":0.0007449012,"domain_scores_codex":[0.9998838,0.00001681452,0.00001099958,0.00002305606,0.00004745483,0.00001793512],"domain_scores_gemma":[0.9998605,0.00005203533,0.00002398093,0.000008701808,0.00003521326,0.00001965247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001692642,0.00006248965,0.0003187828,0.005398851,0.00005571822,0.0006148204,0.00007946262,0.000894985,0.0207488,0.009414752,0.01973134,0.9425108],"study_design_scores_gemma":[0.00002239916,0.00005003721,0.0007578193,0.0005487225,0.00006866561,0.00166959,0.00006030795,0.0001232647,0.005159067,0.003704013,0.9878208,0.00001539509],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005410286,0.9968057,0.000573881,0.0002764239,0.0002204714,0.000003696528,0.00001658192,0.00001809707,0.001544124],"genre_scores_gemma":[0.002547784,0.9952164,0.0005315724,0.0002057773,0.0001867656,0.000008242291,0.00004346753,0.000002181773,0.00125794],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001268618,"threshold_uncertainty_score":0.004604638,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03055921949811746,"score_gpt":0.2786620649293912,"score_spread":0.2481028454312738,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}