{"id":"W2005510817","doi":"10.1074/jbc.m310042200","title":"Rpe65 Is a Retinyl Ester Binding Protein That Presents Insoluble Substrate to the Isomerase in Retinal Pigment Epithelial Cells","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":123,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"RPE65; Pigment; Substrate (aquarium); Retinal; Retinal pigment epithelium; Chemistry; Biochemistry; Isomerase; Enzyme; Biology; Organic chemistry; Ecology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006798431,0.0002098183,0.00022812,0.00003228343,0.00007079217,0.0000498378,0.000362955,0.0002219758,0.0001827902],"category_scores_gemma":[0.0001993257,0.000129761,0.0001515684,0.0001434909,0.00008043701,0.000007486293,0.00009508323,0.0002919477,0.00001590335],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003418015,"about_ca_system_score_gemma":0.0001054604,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003158807,"about_ca_topic_score_gemma":0.000001828645,"domain_scores_codex":[0.9985371,0.0001089203,0.0004594241,0.000287734,0.0002476475,0.0003591664],"domain_scores_gemma":[0.99928,0.0000199754,0.0002616037,0.0002000347,0.00008070968,0.0001576286],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003817025,0.0001164984,0.01510641,0.00001947287,0.00002587279,0.00002999554,0.00006006508,0.00001265681,0.982621,0.000002788691,0.001445011,0.0001785699],"study_design_scores_gemma":[0.0007046538,0.0002513383,0.002007837,0.00006163582,0.000006750061,0.00004952471,0.0002626215,0.000001526137,0.9667435,0.00007210824,0.0296419,0.0001966542],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968955,0.0002908928,0.0000670182,0.0007858917,0.0001008732,0.0002243594,0.000009682583,0.000003154586,0.001622609],"genre_scores_gemma":[0.9972287,0.000235636,0.0005793225,0.0003236622,0.0001281343,0.0000180399,0.000009866542,0.00001143484,0.001465246],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02819689,"threshold_uncertainty_score":0.52915,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02245682640599487,"score_gpt":0.2489596574548747,"score_spread":0.2265028310488799,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}