{"id":"W2005510817","doi":"10.1074/jbc.m310042200","title":"Rpe65 Is a Retinyl Ester Binding Protein That Presents Insoluble Substrate to the Isomerase in Retinal Pigment Epithelial Cells","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":123,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"RPE65; Pigment; Substrate (aquarium); Retinal; Retinal pigment epithelium; Chemistry; Biochemistry; Isomerase; Enzyme; Biology; Organic chemistry; Ecology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001179821,0.0004906878,0.0002790747,0.0002649788,0.0002744238,0.0003236987,0.000203319,0.0004197031,0.00103199],"category_scores_gemma":[0.0001129436,0.0001961503,0.0004383752,0.0002120679,0.0002239482,0.0002598099,0.0003140835,0.0005269292,0.001072962],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002476266,"about_ca_system_score_gemma":0.0001430125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008705482,"about_ca_topic_score_gemma":0.0006328492,"domain_scores_codex":[0.9998423,0.0000192773,0.00001664602,0.00004885908,0.0000438876,0.00002898539],"domain_scores_gemma":[0.9999429,0.000005487022,0.00002038062,0.000008811088,0.00000812273,0.00001436767],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002335326,0.000009666019,0.00009807124,0.00002981153,0.000004263987,0.0000588988,0.000009939022,0.000009378146,0.9987944,0.00005888673,0.00003357947,0.0008697339],"study_design_scores_gemma":[0.00001605104,0.0001946648,0.007219849,0.00001669701,0.00003631817,0.001429416,0.0000452118,0.0005344652,0.981474,0.00009881288,0.008922766,0.00001175987],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9605478,0.01129096,0.02219297,0.0003937176,0.0001848256,0.00007251963,0.001100217,0.0006033873,0.003613537],"genre_scores_gemma":[0.9773865,0.00358207,0.008561893,0.0001483044,0.00003288303,0.00005748367,0.002081167,0.00005651157,0.008093257],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00103199,"threshold_uncertainty_score":0.003452361,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02245682640599487,"score_gpt":0.2489596574548747,"score_spread":0.2265028310488799,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}