{"id":"W2005546810","doi":"10.1021/bi801418s","title":"FRET Conformational Analysis of Calmodulin Binding to Nitric Oxide Synthase Peptides and Enzymes","year":2008,"lang":"en","type":"article","venue":"Biochemistry","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Calmodulin; Chemistry; Enzyme; Nitric oxide synthase; Biochemistry; Förster resonance energy transfer; ATP synthase; Biophysics; Nitric oxide; Biology; Fluorescence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001877505,0.0002876033,0.0004026182,0.0001227906,0.0002694314,0.0002386213,0.0006508935,0.0005186007,0.001351524],"category_scores_gemma":[0.0004887201,0.0001618258,0.000305834,0.0001807068,0.0002908555,0.0003328479,0.0002796609,0.001124241,0.0002336958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004911532,"about_ca_system_score_gemma":0.0001251628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006725015,"about_ca_topic_score_gemma":0.0006344278,"domain_scores_codex":[0.9998367,0.00002869047,0.000005615561,0.0000426865,0.00004485537,0.00004152358],"domain_scores_gemma":[0.999848,0.00005708333,0.00002556357,0.00001569172,0.00002880177,0.00002483644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001260263,0.00005326244,0.0003171899,0.00004828598,0.00001541294,0.00009477199,0.00006573616,0.0006958568,0.996941,0.0003724974,0.00009606569,0.001173893],"study_design_scores_gemma":[0.00003128893,0.0002183935,0.005124215,0.00001473316,0.00001626533,0.0002290233,0.000123561,0.0211077,0.9711037,0.0002659196,0.001745046,0.000020173],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918131,0.0004764467,0.006039672,0.00009544112,0.00002334774,0.00002481382,0.0001491901,0.00004089036,0.001337197],"genre_scores_gemma":[0.9943931,0.0003613165,0.003559808,0.00008341874,0.000006227783,0.00005669107,0.0003407276,0.00003064592,0.00116786],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001351524,"threshold_uncertainty_score":0.00452131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01534337187515479,"score_gpt":0.2589426365539203,"score_spread":0.2435992646787655,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}