{"id":"W2005571237","doi":"10.1074/jbc.m304498200","title":"Hsp10 and Hsp60 Suppress Ubiquitination of Insulin-like Growth Factor-1 Receptor and Augment Insulin-like Growth Factor-1 Receptor Signaling in Cardiac Muscle","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Insulin-like growth factor; HSP60; Biology; Endocrinology; Internal medicine; Growth factor; Signal transduction; Heat shock protein; Insulin receptor; Cell biology; Autophosphorylation; Receptor; Insulin; Kinase; Medicine; Protein kinase A; Hsp70; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008807324,0.0002995314,0.0005635786,0.00008502046,0.00007412652,0.0000408487,0.0002722682,0.0005886367,0.000176747],"category_scores_gemma":[0.001500917,0.0002411148,0.0001652778,0.0001822345,0.0002370594,0.00002339943,0.0001936358,0.0005500419,0.00000144967],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001000632,"about_ca_system_score_gemma":0.0001598286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001447358,"about_ca_topic_score_gemma":0.000001134357,"domain_scores_codex":[0.9975606,0.0003783262,0.0007976571,0.0004584779,0.0003790849,0.0004259168],"domain_scores_gemma":[0.99852,0.0001522533,0.0003606446,0.0002053176,0.0004545985,0.0003072111],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002356881,0.0001786578,0.01304745,0.0001738886,0.00007031963,0.000007424224,0.0001125719,0.000002922471,0.9847699,0.00001147436,0.0001314504,0.001258293],"study_design_scores_gemma":[0.001207939,0.0005969423,0.01136337,0.00008528095,0.00001043404,0.00002346782,0.0002863957,0.000004221088,0.981097,0.00006489992,0.004986215,0.0002738762],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958895,0.003183263,0.00009289555,0.0001201511,0.0001334137,0.0002362217,0.0001121402,0.000006878632,0.0002254712],"genre_scores_gemma":[0.9947851,0.00368085,0.00112569,0.00005159664,0.0001944541,0.00001400061,0.0000556952,0.000022926,0.00006973757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004854765,"threshold_uncertainty_score":0.9832376,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02168357226416643,"score_gpt":0.2681042314384,"score_spread":0.2464206591742335,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}