{"id":"W2005670455","doi":"10.1038/sj.onc.1210652","title":"Sam68 haploinsufficiency delays onset of mammary tumorigenesis and metastasis","year":2007,"lang":"en","type":"article","venue":"Oncogene","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":103,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Jewish General Hospital; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Biology; Carcinogenesis; Cancer research; Oncogene; Mammary tumor; Metastasis; Kinase; Tyrosine kinase; Haploinsufficiency; Protein tyrosine phosphatase; Proto-oncogene tyrosine-protein kinase Src; Signal transduction; Cell biology; Cancer; Cell; Cell cycle; Breast cancer; Phenotype; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005003809,0.00009701209,0.0001311931,0.00006778124,0.00005470407,0.00001001815,0.0001522679,0.00006598284,0.00001556681],"category_scores_gemma":[0.00007667863,0.00008711237,0.00005980684,0.0001251049,0.00007291443,0.000003259831,0.0001216034,0.00004421918,0.000005115197],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009049463,"about_ca_system_score_gemma":0.00007535243,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006229078,"about_ca_topic_score_gemma":0.00007721547,"domain_scores_codex":[0.9991343,0.00002998491,0.0001863818,0.0002283065,0.0001536935,0.0002673239],"domain_scores_gemma":[0.9994601,0.00001986329,0.00005273499,0.0002648847,0.00007370615,0.0001287306],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006729011,0.00006155706,0.003799143,0.00001681095,0.00003827984,0.00002256849,0.00001390266,0.000004876321,0.971064,0.00007620019,0.0003257496,0.02450967],"study_design_scores_gemma":[0.0003153625,0.0003972205,0.007784842,0.000006832868,0.00001545451,0.0000716486,0.00007097453,0.00004837129,0.9846182,0.00002912851,0.006518691,0.0001233002],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854977,0.002900151,0.009879494,0.0000646965,0.00003439018,0.00008380888,0.0000232768,0.000005040766,0.001511503],"genre_scores_gemma":[0.9937036,0.0007243811,0.004450182,0.00009211928,0.00005611333,0.000002590935,0.00002455558,0.0000122677,0.0009341577],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02438637,"threshold_uncertainty_score":0.3552339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.013041250939503,"score_gpt":0.2811816602675137,"score_spread":0.2681404093280107,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}