{"id":"W2005670455","doi":"10.1038/sj.onc.1210652","title":"Sam68 haploinsufficiency delays onset of mammary tumorigenesis and metastasis","year":2007,"lang":"en","type":"article","venue":"Oncogene","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":103,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Jewish General Hospital; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Biology; Carcinogenesis; Cancer research; Oncogene; Mammary tumor; Metastasis; Kinase; Tyrosine kinase; Haploinsufficiency; Protein tyrosine phosphatase; Proto-oncogene tyrosine-protein kinase Src; Signal transduction; Cell biology; Cancer; Cell; Cell cycle; Breast cancer; Phenotype; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001981545,0.0005119613,0.0004056006,0.000955224,0.000292584,0.0004887969,0.0005410418,0.0004806943,0.005097845],"category_scores_gemma":[0.0002424066,0.0004595025,0.0002548749,0.0002917737,0.0004395615,0.000354297,0.0004820367,0.0009095992,0.001010673],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003634235,"about_ca_system_score_gemma":0.0003642949,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00102286,"about_ca_topic_score_gemma":0.002544353,"domain_scores_codex":[0.9997147,0.00003921275,0.00003220082,0.00006553337,0.00006562925,0.00008266075],"domain_scores_gemma":[0.9994271,0.0001168299,0.0001536228,0.00007287959,0.00003103317,0.0001986891],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001570556,0.00002314664,0.0001397317,0.0000131536,0.000002764287,0.00009003174,0.000008574923,0.00004099603,0.997894,0.0002069367,0.00006618712,0.001357472],"study_design_scores_gemma":[0.00001831365,0.0001751638,0.003103531,0.000005044657,0.000009234785,0.0005541265,0.00004922502,0.0007129511,0.9920419,0.0001195631,0.003204694,0.000006245923],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907545,0.00178728,0.003564895,0.0002653969,0.0001309053,0.00002136875,0.0007143922,0.0005440851,0.002217231],"genre_scores_gemma":[0.9877994,0.0005883634,0.002262685,0.0000747988,0.00002813016,0.00002515571,0.0005192074,0.0001625102,0.008539808],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005097845,"threshold_uncertainty_score":0.01705396,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.013041250939503,"score_gpt":0.2811816602675137,"score_spread":0.2681404093280107,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}