{"id":"W2005678905","doi":"10.1016/j.mimet.2010.03.015","title":"Perspective: Researching the transition from non-living to the first microorganisms: Methods and experiments are major challenges","year":2010,"lang":"en","type":"article","venue":"Journal of Microbiological Methods","topic":"Origins and Evolution of Life","field":"Physics and Astronomy","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Abiogenesis; Three-domain system; Experimental evolution; Biology; Perspective (graphical); Biochemical engineering; Data science; Computer science; Computational biology; Cognitive science; Genome; Astrobiology; Psychology; Genetics; Artificial intelligence; Engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003547848,0.0001545004,0.0002927045,0.00005232408,0.000418992,0.00009356985,0.000387185,0.00007816908,0.0003119282],"category_scores_gemma":[0.0001977071,0.00007414827,0.0001586618,0.00009448836,0.0001391773,0.0000903003,0.000131794,0.0008079692,0.00000484957],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003193637,"about_ca_system_score_gemma":0.00002655266,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009737076,"about_ca_topic_score_gemma":0.00001413739,"domain_scores_codex":[0.9982167,0.0009323511,0.0003185389,0.0002126767,0.00008765417,0.0002320372],"domain_scores_gemma":[0.9980108,0.001293653,0.0002311915,0.000198427,0.0001571676,0.0001087328],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004972882,0.0001130797,0.0004617164,0.000003532043,0.000141771,0.00000144793,0.006267385,0.00001221978,0.9658225,0.001185863,0.001011081,0.02492963],"study_design_scores_gemma":[0.001928468,0.001045999,0.1561779,0.0004872247,0.0002882346,0.00014481,0.09797138,0.0003200178,0.4203617,0.02801714,0.2923278,0.0009293798],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7032906,0.002021963,0.2707383,0.02256589,0.0007097381,0.0002248464,0.00004230351,0.000008713035,0.0003976081],"genre_scores_gemma":[0.6049244,0.00006874445,0.3934964,0.0003485489,0.001116102,0.00000658305,6.162068e-7,0.00001122548,0.00002735775],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5454609,"threshold_uncertainty_score":0.3510269,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04360571994188387,"score_gpt":0.4103447321423614,"score_spread":0.3667390122004776,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}