{"id":"W2005740166","doi":"10.1002/cne.10522","title":"Patterned Purkinje cell degeneration in mouse models of Niemann‐Pick type C disease","year":2003,"lang":"en","type":"article","venue":"The Journal of Comparative Neurology","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":224,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Purkinje cell; Biology; Cerebellum; Programmed cell death; Neuroscience; Neurodegeneration; Niemann–Pick disease, type C; Immunocytochemistry; NPC1; Neuropathology; Pathology; Cell biology; Disease; Endocrinology; Genetics; Medicine; Apoptosis; Intracellular","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004296551,0.0001037967,0.0003664027,0.0001724721,0.00002987267,0.000004736019,0.000160272,0.00004552828,0.00008393105],"category_scores_gemma":[0.00008527363,0.00006803747,0.00006426891,0.0002091685,0.0001210575,0.00009425553,0.00002485198,0.0004141556,0.00000968665],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002369578,"about_ca_system_score_gemma":0.0001918342,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001228177,"about_ca_topic_score_gemma":0.00002714468,"domain_scores_codex":[0.9981797,0.0008302276,0.0004165206,0.00009112655,0.000302877,0.0001795461],"domain_scores_gemma":[0.9989289,0.0001842005,0.0002491627,0.0001877819,0.0003396287,0.0001103349],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.03882401,0.003856794,0.1756421,0.0002404439,0.0002232223,0.0008182652,0.01086362,0.1870252,0.5720362,0.004296669,0.005904495,0.0002689468],"study_design_scores_gemma":[0.03081082,0.02586302,0.2049381,0.0001475334,0.0006708661,0.001309177,0.001595418,0.06200617,0.6435864,0.02380004,0.004440547,0.0008318833],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959232,0.001019045,0.0008500966,0.001149596,0.00008730925,0.0002386964,0.000001759723,0.000002781246,0.0007275478],"genre_scores_gemma":[0.9990231,0.0001515351,0.00006510536,0.0004957704,0.0000359876,0.000001787549,0.00000156347,0.00001033708,0.0002148025],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.125019,"threshold_uncertainty_score":0.2774488,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06993029520312675,"score_gpt":0.330031598174528,"score_spread":0.2601013029714012,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}