{"id":"W2005740166","doi":"10.1002/cne.10522","title":"Patterned Purkinje cell degeneration in mouse models of Niemann‐Pick type C disease","year":2003,"lang":"en","type":"article","venue":"The Journal of Comparative Neurology","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":224,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Purkinje cell; Biology; Cerebellum; Programmed cell death; Neuroscience; Neurodegeneration; Niemann–Pick disease, type C; Immunocytochemistry; NPC1; Neuropathology; Pathology; Cell biology; Disease; Endocrinology; Genetics; Medicine; Apoptosis; Intracellular","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004062147,0.001169131,0.0005071515,0.002261125,0.0005505211,0.0006479964,0.0005986171,0.001223019,0.002559789],"category_scores_gemma":[0.000257003,0.0006274571,0.0004201623,0.0005760064,0.0006930121,0.0005323744,0.000552347,0.001384219,0.0008967061],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001000623,"about_ca_system_score_gemma":0.0004366121,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001859081,"about_ca_topic_score_gemma":0.003848776,"domain_scores_codex":[0.9994323,0.00008658954,0.00006745549,0.0001534628,0.0001754272,0.00008487637],"domain_scores_gemma":[0.9995648,0.00004669272,0.0001609814,0.0000629056,0.0000308625,0.0001336998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004698603,0.0002498573,0.0006393979,0.000122823,0.00004614377,0.00069716,0.0001151246,0.0005747441,0.9934829,0.0008581292,0.00029823,0.002445662],"study_design_scores_gemma":[0.0004577921,0.002181782,0.01795508,0.0001468879,0.0002263879,0.00508731,0.0001733551,0.00493978,0.9544227,0.001295228,0.01305129,0.00006230573],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9815985,0.004188404,0.00651402,0.0003516208,0.0001074831,0.000250367,0.002113466,0.0009019192,0.003974183],"genre_scores_gemma":[0.973788,0.003957561,0.009018524,0.0001715984,0.00001844334,0.0004854994,0.001953504,0.000178994,0.01042782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002559789,"threshold_uncertainty_score":0.00856334,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06993029520312675,"score_gpt":0.330031598174528,"score_spread":0.2601013029714012,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}