{"id":"W2005745083","doi":"10.1002/ana.20381","title":"Unusual variants of Alexander's disease","year":2005,"lang":"en","type":"article","venue":"Annals of Neurology","topic":"RNA regulation and disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":137,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Neurological Disorders and Stroke","keywords":"Magnetic resonance imaging; Pathology; White matter; Glial fibrillary acidic protein; Brainstem; Basal ganglia; Central nervous system disease; Medicine; Disease; Leukoencephalopathy; Radiology; Central nervous system; Internal medicine; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002280535,0.0007872611,0.0006787977,0.0008213323,0.0005275644,0.000515462,0.000424721,0.0007681439,0.002117731],"category_scores_gemma":[0.002253723,0.00026714,0.000301143,0.000666939,0.0007933555,0.0004122812,0.0005708585,0.0005661125,0.0004997832],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001954049,"about_ca_system_score_gemma":0.0001868734,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004355218,"about_ca_topic_score_gemma":0.0008482149,"domain_scores_codex":[0.9995455,0.00006565289,0.00006622071,0.0001239785,0.00007907966,0.0001194279],"domain_scores_gemma":[0.9983339,0.0005455259,0.0005794259,0.0001019058,0.0001201536,0.0003191032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"observational","study_design_scores_codex":[0.0005802252,0.0001477491,0.3091552,0.0002169043,0.0001610355,0.6106141,0.001834741,0.0009892343,0.05207173,0.002477903,0.001236189,0.02051491],"study_design_scores_gemma":[0.00003203271,0.0001676334,0.06271776,0.00001436945,0.00004299207,0.9317151,0.0002126031,0.0003178011,0.002215809,0.0008183632,0.001719066,0.00002645903],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969161,0.0005534385,0.0009109616,0.0001070563,0.00002423518,0.000006854267,0.00005172183,0.00003764523,0.00139197],"genre_scores_gemma":[0.998906,0.0001566801,0.0004324008,0.00005751253,0.00005647484,0.000003451492,0.00006430554,0.00000954259,0.0003136556],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002117731,"threshold_uncertainty_score":0.007084489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03126026538417475,"score_gpt":0.3077188064728612,"score_spread":0.2764585410886864,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}