{"id":"W2005749175","doi":"10.1021/ol050677x","title":"<i>C</i>-Linked Galactosyl Serine AFGP Analogues as Potent Recrystallization Inhibitors","year":2005,"lang":"en","type":"article","venue":"Organic Letters","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"National Institute of General Medical Sciences","keywords":"Chemistry; Antifreeze; Recrystallization (geology); Antifreeze protein; Moiety; Stereochemistry; Serine; Olefin metathesis; Biochemistry; Combinatorial chemistry; Metathesis; Organic chemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001368587,0.0003654139,0.0002947586,0.0001244408,0.0001093161,0.0002048227,0.0003026925,0.0002084521,0.0010002],"category_scores_gemma":[0.0001364259,0.0001013823,0.0001644368,0.0001553973,0.0002021599,0.0002122305,0.0001338618,0.0005052612,0.0002930583],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002608121,"about_ca_system_score_gemma":0.0001329392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005280635,"about_ca_topic_score_gemma":0.000732458,"domain_scores_codex":[0.999912,0.00002164388,0.000006636636,0.00001300821,0.00002071726,0.00002595022],"domain_scores_gemma":[0.9999191,0.00001642482,0.00002644795,0.000008415661,0.00001173115,0.00001795206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002637964,0.00004199755,0.00006213042,0.00006309727,0.00000791191,0.0001102321,0.00002053997,0.000303768,0.9957658,0.0002684632,0.00009826734,0.002994068],"study_design_scores_gemma":[0.0000658616,0.001027495,0.0004377171,0.000005486935,0.00001454715,0.000231397,0.00000806082,0.000240294,0.9950128,0.00002578134,0.002924063,0.000006465189],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9870992,0.00430062,0.00332487,0.00009590486,0.00003905651,0.0001076747,0.0002312109,0.00009555811,0.00470588],"genre_scores_gemma":[0.9930564,0.00186567,0.002957298,0.00005809518,0.00001327513,0.00004380739,0.0002970423,0.00002144483,0.001687015],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0010002,"threshold_uncertainty_score":0.003345966,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01416376219605438,"score_gpt":0.264778676262931,"score_spread":0.2506149140668766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}