{"id":"W2005767212","doi":"10.4161/rna.2.1.1368","title":"Lost Once, the Fragile X Mental Retardation Protein is Now Back onto Brain Polyribosomes","year":2005,"lang":"en","type":"article","venue":"RNA Biology","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Saint-François d'Assise","funders":"","keywords":"Biology; Polysome; Fragile x; Translation (biology); Fragile X syndrome; Protein biosynthesis; Genetics; Ribosome; Computational biology; RNA; Messenger RNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001031321,0.0001647975,0.0001124377,0.00002591032,0.0001077965,0.00001757901,0.0002545476,0.0001507694,0.000453271],"category_scores_gemma":[0.00002231344,0.0001244897,0.00007262052,0.0000676863,0.0001263644,0.000003543014,0.0001451558,0.00008663186,0.0004459117],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001802217,"about_ca_system_score_gemma":0.0000501424,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002186765,"about_ca_topic_score_gemma":0.0002261415,"domain_scores_codex":[0.9990188,0.00007646093,0.0001918568,0.0003644038,0.0000724892,0.0002759784],"domain_scores_gemma":[0.9995471,0.000008242596,0.00007394368,0.0002857762,0.00003111406,0.00005381931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003684486,0.00004354068,0.001148768,0.000003454156,0.00003135009,2.007794e-7,0.00007733774,0.000003226877,0.9555529,0.0000833218,0.03671978,0.006299312],"study_design_scores_gemma":[0.0003473376,0.0001925417,0.004548223,0.00000392531,0.000003684666,0.000005154751,0.00004318035,0.00003273,0.468621,0.00007803492,0.5259782,0.0001459387],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.97927,0.0008311899,0.00009534619,0.01343707,0.000139162,0.0003794768,0.00006551571,0.000007624227,0.005774653],"genre_scores_gemma":[0.9849713,0.0003231934,0.0006219429,0.005654656,0.0001123954,0.00002553289,0.0003114756,0.00001950489,0.007959997],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4892584,"threshold_uncertainty_score":0.5731442,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008513278024205007,"score_gpt":0.2403854656658623,"score_spread":0.2318721876416573,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}