{"id":"W2005819950","doi":"10.1016/j.clinthera.2005.03.006","title":"The CONCEPT trial: A 1-year, multicenter, randomized,double-blind, double-dummy comparison of a stable dosing regimen of salmeterol/fluticasone propionate with an adjustable maintenance dosing regimen of formoterol/budesonide in adults with persistent asthma","year":2005,"lang":"en","type":"article","venue":"Clinical Therapeutics","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":100,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Vancouver General Hospital","funders":"","keywords":"Medicine; Formoterol; Salmeterol; Regimen; Dosing; Budesonide/formoterol; Fluticasone propionate; Budesonide; Randomized controlled trial; Double blind; Fluticasone; Pharmacology; Internal medicine; Corticosteroid; Asthma; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001966691,0.0003836819,0.001970223,0.0001311449,0.0001211954,0.00003594284,0.0003540755,0.0002350016,0.00001460392],"category_scores_gemma":[0.0001029353,0.0002114141,0.0004518529,0.000373634,0.00160523,0.0002435816,0.00008077101,0.0005490846,0.000001205323],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001068565,"about_ca_system_score_gemma":0.0003947642,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000088997,"about_ca_topic_score_gemma":0.0001323327,"domain_scores_codex":[0.9953622,0.0005743096,0.002163691,0.0005386772,0.0007591081,0.0006020511],"domain_scores_gemma":[0.9958149,0.0009555919,0.001497476,0.000850977,0.000621185,0.0002598837],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9692908,0.003215483,0.008466094,0.0002384605,0.0006815261,0.000008461849,0.001858836,0.0006653684,0.0002035395,0.0001836403,0.00001935799,0.01516844],"study_design_scores_gemma":[0.9548504,0.01079936,0.0006334772,0.003002763,0.0009740106,0.0000116324,0.006352674,0.01692914,0.004132816,0.00001324116,0.001984565,0.0003158742],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901538,0.003735011,0.0008626398,0.0006230111,0.0001052147,0.004241205,0.00001538499,0.00003632878,0.0002273475],"genre_scores_gemma":[0.9931086,0.000521171,0.005623221,0.0002347771,0.0001263103,0.00009349347,0.00001667021,0.00006728719,0.0002084994],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01626377,"threshold_uncertainty_score":0.8621217,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08122762669967477,"score_gpt":0.3774367020759708,"score_spread":0.296209075376296,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}