{"id":"W2005823056","doi":"10.1038/sj.bjp.0707588","title":"Control of left ventricular mass by moxonidine involves reduced DNA synthesis and enhanced DNA fragmentation","year":2007,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Renin-Angiotensin System Studies","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Moxonidine; Internal medicine; DNA fragmentation; Endocrinology; Left ventricular hypertrophy; Blood pressure; Ventricular pressure; Chemistry; Apoptosis; Medicine; Agonist; Programmed cell death; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001176665,0.0003502915,0.0003090355,0.0001937822,0.0001112328,0.0001605555,0.0001716273,0.0002958406,0.001435041],"category_scores_gemma":[0.0001052911,0.0001226642,0.0002602482,0.00007286629,0.0002669028,0.0002017247,0.0001089386,0.000531783,0.0001790595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002059705,"about_ca_system_score_gemma":0.0001563558,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002102432,"about_ca_topic_score_gemma":0.0004255348,"domain_scores_codex":[0.9998988,0.0000169882,0.00001246636,0.00002660811,0.00002341159,0.00002174122],"domain_scores_gemma":[0.9998589,0.00001500664,0.00006881096,0.00001202537,0.00001474256,0.00003059461],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003705255,0.00004262142,0.0002077403,0.00003977049,0.000005036158,0.00002256576,0.00000718976,0.00001311558,0.9983066,0.00001846919,0.00001067378,0.0009557369],"study_design_scores_gemma":[0.00007376271,0.003418251,0.01509753,0.00001508356,0.00002145741,0.0002757564,0.00002668445,0.0002741833,0.9799541,0.00003559761,0.0008028693,0.000004767757],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951078,0.00264573,0.001244003,0.00006808888,0.00003517942,0.00003551015,0.0001725098,0.00004448499,0.0006467287],"genre_scores_gemma":[0.9959071,0.001080513,0.001420227,0.00005657447,0.00002288736,0.00005867143,0.000252217,0.00000778387,0.001193927],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001435041,"threshold_uncertainty_score":0.004800677,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009135198641955939,"score_gpt":0.2816034141990038,"score_spread":0.2724682155570479,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}