{"id":"W2005851491","doi":"10.1016/j.tiv.2009.12.002","title":"2,3,7,8-Tetrachlorodibenzo-p-dioxin and β-naphthoflavone induce cellular hypertrophy in H9c2 cells by an aryl hydrocarbon receptor-dependant mechanism","year":2009,"lang":"en","type":"article","venue":"Toxicology in Vitro","topic":"Eicosanoids and Hypertension Pharmacology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Aryl hydrocarbon receptor; CYP1B1; Chemistry; Internal medicine; Atrial natriuretic peptide; Endocrinology; In vivo; Receptor; Oxidative stress; Gene expression; Pharmacology; Cytochrome P450; Transcription factor; Biology; Gene; Biochemistry; Medicine; Metabolism","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000250677,0.0005302634,0.0003898086,0.0005396925,0.000292415,0.0002794461,0.000199764,0.0004158377,0.001590908],"category_scores_gemma":[0.0001239096,0.0003558937,0.0005592728,0.0002882907,0.0003529273,0.0002905634,0.0002625909,0.0007591843,0.0006112046],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004013641,"about_ca_system_score_gemma":0.0002918112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001476896,"about_ca_topic_score_gemma":0.002805487,"domain_scores_codex":[0.9997148,0.00005602144,0.00002597182,0.00003362455,0.00006138398,0.0001081998],"domain_scores_gemma":[0.9997484,0.00004855401,0.00003822518,0.00005119394,0.00003634847,0.00007724704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002781415,0.00004937468,0.0001483776,0.00001141138,0.000005090516,0.000071321,0.00001463593,0.00002031369,0.9990317,0.00004412558,0.00002288249,0.0003026935],"study_design_scores_gemma":[0.00004831214,0.0009630625,0.0105765,0.000005051174,0.00001847868,0.0002115882,0.00006909263,0.0003553321,0.9867641,0.00007495966,0.0009075666,0.000005962804],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925327,0.002104884,0.002183681,0.0002215895,0.000163743,0.00004553085,0.0003406153,0.0001044415,0.002302834],"genre_scores_gemma":[0.9916131,0.001688038,0.001121637,0.0001573706,0.0000681547,0.00005604548,0.0007056926,0.00002409344,0.004565837],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001590908,"threshold_uncertainty_score":0.005322099,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009479431241364933,"score_gpt":0.241401228880211,"score_spread":0.2319217976388461,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}