{"id":"W2005854629","doi":"10.1021/la050710o","title":"Active Loading and Tunable Release of Doxorubicin from Block Copolymer Vesicles","year":2005,"lang":"en","type":"article","venue":"Langmuir","topic":"Advanced Polymer Synthesis and Characterization","field":"Chemistry","cited_by":178,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Copolymer; Vesicle; Doxorubicin; Block (permutation group theory); Chemistry; Chemical engineering; Polymer chemistry; Materials science; Organic chemistry; Membrane; Polymer; Biochemistry; Engineering; Chemotherapy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001873741,0.0003212356,0.0002673454,0.0001280667,0.00009736474,0.0003154195,0.0001993313,0.000255049,0.0004091686],"category_scores_gemma":[0.0002163004,0.0001580014,0.0001910283,0.00009055423,0.0001753021,0.0003543507,0.000270192,0.0003106617,0.0002634663],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003054031,"about_ca_system_score_gemma":0.0001154932,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002152068,"about_ca_topic_score_gemma":0.0003202106,"domain_scores_codex":[0.9998571,0.00002239265,0.0000175818,0.00003966368,0.000037332,0.00002587131],"domain_scores_gemma":[0.9998775,0.00003173029,0.00003609713,0.00001576439,0.00001634303,0.00002254684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002620418,0.000005287091,0.00001757974,0.00001839499,0.000001499716,0.00001012425,0.000004854484,0.00006054114,0.9991758,0.00005597005,0.000008225836,0.0006154657],"study_design_scores_gemma":[0.000007977521,0.0000524775,0.0001938227,0.000002506452,0.000004711183,0.00002436707,0.00000192412,0.0005627684,0.9986718,0.00001193822,0.0004633692,0.000002399601],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9870656,0.00198299,0.009451708,0.00005784336,0.00002273528,0.0000368839,0.0001866943,0.00009968812,0.001095907],"genre_scores_gemma":[0.9910286,0.001068984,0.006060931,0.00002191996,0.00001044126,0.0000305087,0.0001751308,0.00003430551,0.001569296],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004091686,"threshold_uncertainty_score":0.002215862,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006873262035204003,"score_gpt":0.2136701808518917,"score_spread":0.2067969188166877,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}