{"id":"W2005854690","doi":"10.1002/em.21695","title":"Influence of arylamine <i>n</i>‐acetyltransferase, sex, and age on 4‐aminobiphenyl‐induced in vivo mutant frequencies and spectra in mouse liver","year":2012,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Liver tumor; Internal medicine; Endocrinology; Biology; In vivo; CYP1A2; Carcinogen; Mutant; Nat; Carcinogenesis; DNA adduct; 2-Acetylaminofluorene; Cytochrome P450; Molecular biology; Cancer; Genetics; In vitro; Metabolism; Medicine; Hepatocellular carcinoma; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003652164,0.0005735016,0.0003145189,0.0008258719,0.0001891456,0.0003355131,0.0002750989,0.0005072895,0.00184236],"category_scores_gemma":[0.0002592573,0.0003509401,0.000399527,0.0002258854,0.0003301537,0.0003794196,0.0002307486,0.0006817624,0.0004787176],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002736017,"about_ca_system_score_gemma":0.0002051256,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009242209,"about_ca_topic_score_gemma":0.001691236,"domain_scores_codex":[0.9994977,0.0001243506,0.0000548568,0.0001377615,0.00008674572,0.00009870224],"domain_scores_gemma":[0.9992989,0.0001241362,0.0002094491,0.00006924911,0.00007477538,0.0002234357],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008399492,0.0001001009,0.0009049958,0.00001443458,0.000007896701,0.00003628542,0.00003388669,0.0000301129,0.9970556,0.00002385553,0.00001899443,0.0009338913],"study_design_scores_gemma":[0.00003006482,0.002564032,0.02005134,0.000007532819,0.00004885838,0.0002026982,0.00006677015,0.0003631008,0.9757853,0.00003904375,0.0008278582,0.00001343236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962954,0.0007603508,0.001243025,0.0000624716,0.00002674821,0.00004221158,0.0005143461,0.00008201422,0.0009734439],"genre_scores_gemma":[0.9900786,0.0009010769,0.001631388,0.000117048,0.00001984588,0.0001559282,0.0008598772,0.00009206261,0.006144225],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00184236,"threshold_uncertainty_score":0.006163299,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005949362468788924,"score_gpt":0.1983591270416354,"score_spread":0.1924097645728464,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}